Reactome | TAS2R40 [plasma membrane]

TAS2R40 [plasma membrane]

Stable Identifier

R-GGA-3299615-2

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

TAS2R16, A0A8V1ABD5

Locations in the PathwayBrowser

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Sensory Perception (Gallus gallus)

- Sensory perception of taste (Gallus gallus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Gallus gallus)
    - Bitter compound binds bitter taste receptor (TAS2R) (Gallus gallus)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Gallus gallus)
        
        TAS2R (non-orphan) [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Gallus gallus)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Gallus gallus)
        
        TAS2R16:ligand [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Gallus gallus)
      - T2Rs bind bitter-tasting compounds (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Gallus gallus)
        
        TAS2Rs [plasma membrane] (Gallus gallus)
        
        Homologues of TAS2R16 [plasma membrane] (Gallus gallus)
        
        TAS2R40 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V1ABD5

Gene Names

TAS2R40

Reference Genes

BioGPS Gene:101749182 TAS2R40

ENSEMBL:ENSGALG00010025667.1

Monarch:101749182 TAS2R40

NCBI Gene:101749182 TAS2R40

UCSC:A0A8V1ABD5 TAS2R40

Reference Transcript

RefSeq:NM_001396669.1 TAS2R40

Other Identifiers

101749182

GO:0001580

GO:0004930

GO:0007165

GO:0007186

GO:0016020

GO:0033038

GO:0050877

GO:0050909

Participates

as a member of

Homologues of TAS2R16 [plasma membrane] (Gallus gallus)

Other forms of this molecule

TAS2R40 [plasma membrane]

Inferred From

TAS2R16 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001383598.1

ENSEMBL

ENSGALG00010025667, ENSGALP00010038742, ENSGALT00010062658