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PTEN [cytosol]
Stable Identifier
R-GGA-199420
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
PTEN, A0A8V0ZJ28
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
TCR signaling (Gallus gallus)
Downstream TCR signaling (Gallus gallus)
PTEN dephosphorylates PIP3 (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
Metabolism (Gallus gallus)
Inositol phosphate metabolism (Gallus gallus)
Synthesis of IP3 and IP4 in the cytosol (Gallus gallus)
I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Gallus gallus)
PTEN:Mg2+ [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Phospholipid metabolism (Gallus gallus)
PI Metabolism (Gallus gallus)
Synthesis of PIPs at the plasma membrane (Gallus gallus)
PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN dephosphorylates PIP3 (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Ovarian tumor domain proteases (Gallus gallus)
OTUD3 deubiquitinates PTEN (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PTEN dephosphorylates PIP3 (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN Regulation (Gallus gallus)
Regulation of PTEN localization (Gallus gallus)
Deubiquitinated PTEN translocates to the cytosol (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN undergoes monoubiquitination (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
Regulation of PTEN stability and activity (Gallus gallus)
FRK phosphorylates PTEN (Gallus gallus)
PTEN:p-Y387-FRK [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
MKRN1 polyubiquitinates PTEN (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PREX2 binds PTEN and inhibits it (Gallus gallus)
PREX2:PTEN,p-3S,2T-PTEN [cytosol] (Gallus gallus)
PTEN, p-3S,2T-PTEN [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN, p-3S,2T-PTEN [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN binds FRK (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN:p-Y387-FRK [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
TNKS and TNKS2 PARylate PTEN (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
TRIM27 binds PTEN (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
PTEN:TRIM27 [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
TRIM27 polyubiquitinates PTEN (Gallus gallus)
PTEN:TRIM27 [cytosol] (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
USP13 and OTUD3 deubiquitinate PTEN (Gallus gallus)
PTEN [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0ZJ28
Gene Names
PTEN
Reference Genes
BioGPS Gene:423675 PTEN
ENSEMBL:ENSGALG00010022667.1
Monarch:423675 PTEN
NCBI Gene:423675 PTEN
UCSC:A0A8V0ZJ28 PTEN
Reference Transcript
RefSeq:XM_040702867.2 PTEN
RefSeq:XM_040674795.2 PTEN
Other Identifiers
423675
GO:0001649
GO:0003824
GO:0004438
GO:0004721
GO:0004722
GO:0004725
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006355
GO:0006629
GO:0006915
GO:0007010
GO:0007056
GO:0007399
GO:0008013
GO:0008285
GO:0009898
GO:0009966
GO:0010604
GO:0010648
GO:0010719
GO:0010997
GO:0014069
GO:0016311
GO:0016314
GO:0016324
GO:0016605
GO:0016787
GO:0016791
GO:0019899
GO:0022414
GO:0023057
GO:0030154
GO:0030165
GO:0030336
GO:0030351
GO:0031647
GO:0042802
GO:0042995
GO:0043197
GO:0043226
GO:0043491
GO:0045202
GO:0045595
GO:0045668
GO:0045944
GO:0046856
GO:0048856
GO:0048870
GO:0050821
GO:0051093
GO:0051129
GO:0051241
GO:0051548
GO:0051717
GO:0051726
GO:0051800
GO:0051895
GO:0051896
GO:0051898
GO:0052866
GO:0065008
GO:0071257
GO:0140096
GO:1902533
GO:1902807
GO:1903690
GO:1904706
GO:1990381
GO:2000060
GO:2000134
GT_A_87_P080156
GgaAffx.25913.1.S1_at
Participates
as an output of
OTUD3 deubiquitinates PTEN (Gallus gallus)
USP13 and OTUD3 deubiquitinate PTEN (Gallus gallus)
Deubiquitinated PTEN translocates to the cytosol (Gallus gallus)
as a member of
PTEN, p-3S,2T-PTEN [cytosol] (Gallus gallus)
as an input of
MKRN1 polyubiquitinates PTEN (Gallus gallus)
TNKS and TNKS2 PARylate PTEN (Gallus gallus)
PTEN binds FRK (Gallus gallus)
TRIM27 binds PTEN (Gallus gallus)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Gallus gallus)
PTEN undergoes monoubiquitination (Gallus gallus)
as a component of
PTEN:p-Y387-FRK [cytosol] (Gallus gallus)
PTEN:TRIM27 [cytosol] (Gallus gallus)
PTEN:Mg2+ [cytosol] (Gallus gallus)
Other forms of this molecule
PTEN [cytosol]
PTEN [nucleoplasm]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
phospho-PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [cytosol]
PTEN [nucleoplasm]
PTEN [nucleoplasm]
Inferred From
PTEN [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_040530729.1
,
XP_040558801.1
ENSEMBL
ENSGALP00010033357
,
ENSGALT00010055143
,
ENSGALG00010022667
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