Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SRGAP2 [cytosol]
Stable Identifier
R-GGA-195131
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
SRGAP2, A0A8V1ACI3
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate Formins (Gallus gallus)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
CDC42 GTPase cycle (Gallus gallus)
CDC42 GAPs stimulate CDC42 GTPase activity (Gallus gallus)
CDC42 GAPs [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 GAPs stimulate RAC1 GTPase activity (Gallus gallus)
RAC1 GAPs [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RAC3 GTPase cycle (Gallus gallus)
RAC3 GAPs stimulate RAC3 GTPase activity (Gallus gallus)
RAC3 GAPs [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RHOF GTPase cycle (Gallus gallus)
RHOF GAPs stimulate RHOF GTPase activity (Gallus gallus)
RHOF GAPs [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RHOQ GTPase cycle (Gallus gallus)
RHOQ GAPs stimulate RHOQ GTPase activity (Gallus gallus)
RHOQ GAPs [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RHOU GTPase cycle (Gallus gallus)
RHOU binds effectors at the plasma membrane (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
RHOU:GTP:RHOU effectors [plasma membrane] (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
SRGAP2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V1ACI3
Gene Names
SRGAP2
Reference Genes
BioGPS Gene:419843 SRGAP2
ENSEMBL:ENSGALG00010027097.1
KEGG:gga:419843 SRGAP2
Monarch:419843 SRGAP2
NCBI Gene:419843 SRGAP2
UCSC:A0A8V1ACI3 SRGAP2
Reference Transcript
RefSeq:XM_046933105.1 SRGAP2
RefSeq:XM_040691209.2 SRGAP2
RefSeq:XM_025143891.3 SRGAP2
RefSeq:XM_004934954.5 SRGAP2
Other Identifiers
419843
GO:0005096
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0007010
GO:0007165
GO:0007399
GO:0014069
GO:0016020
GO:0021816
GO:0030027
GO:0030334
GO:0031267
GO:0031410
GO:0034330
GO:0042803
GO:0042995
GO:0043197
GO:0043226
GO:0045202
GO:0045211
GO:0045335
GO:0046847
GO:0048812
GO:0048856
GO:0051963
GO:0060996
GO:0098772
GO:0098978
GO:1904861
GO:1904862
GT_A_87_P063581
GgaAffx.22214.1.S1_s_at
Participates
as a candidate of
RHOQ GAPs [cytosol] (Gallus gallus)
CDC42 GAPs [cytosol] (Gallus gallus)
RHOF GAPs [cytosol] (Gallus gallus)
RAC3 GAPs [cytosol] (Gallus gallus)
RHOU effectors [cytosol] (Gallus gallus)
as a member of
RAC1 GAPs [cytosol] (Gallus gallus)
as an output of
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Gallus gallus)
as an input of
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Gallus gallus)
as a component of
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Gallus gallus)
Inferred From
SRGAP2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_004935011.1
,
XP_024999659.1
,
XP_040547143.1
,
XP_046789061.1
ENSEMBL
ENSGALP00010039941
,
ENSGALT00010065675
,
ENSGALG00010027097
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text