Reactome | phospho-GAB1 [cytosol]

phospho-GAB1 [cytosol]

Stable Identifier

R-GGA-180496

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

p-Y627,Y659-GAB1, A0A8V0Y2H6

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by Receptor Tyrosine Kinases (Gallus gallus)
  - Signaling by EGFR (Gallus gallus)
    - GAB1 signalosome (Gallus gallus)
      - Dephosphorylation of Gab1 by SHP2 (Gallus gallus)
        
        EGF-like ligands:p-6Y-EGFR:GRB2:p-Y627,659-GAB1:SHP2 [plasma membrane] (Gallus gallus)
        
        GRB2:p-Y627,Y659-GAB1,GRB2:p-Y627,Y659-GAB1:PIP3 [plasma membrane] (Gallus gallus)
        
        GRB2:Phospho-GAB1(partially dephosphorylated) [cytosol] (Gallus gallus)
        
        phospho-GAB1 [cytosol] (Gallus gallus)
        
        GRB2:p-GAB1(partially dephosphorylated):PIP3 [plasma membrane] (Gallus gallus)
        
        GRB2:Phospho-GAB1(partially dephosphorylated) [cytosol] (Gallus gallus)
        
        phospho-GAB1 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0Y2H6

Gene Names

GAB1

Reference Genes

BioGPS Gene:422456 GAB1

ENSEMBL:ENSGALG00010007898.1

Monarch:422456 GAB1

NCBI Gene:422456 GAB1

UCSC:A0A8V0Y2H6 GAB1

Reference Transcript

Other Identifiers

422456

GO:0001525

GO:0005737

GO:0005911

GO:0007165

GO:0035591

GO:0035767

GO:0038084

GO:0045766

GO:0048870

GO:0060090

GT_A_87_P015560

GT_A_87_P094941

GT_A_87_P126083

GT_Xhyb_Chicken_CO760810_4252

Gga.15954.1.S1_at

Gga.19508.1.S1_s_at

GgaAffx.23069.1.S1_s_at

Participates

as a component of

GRB2:Phospho-GAB1(partially dephosphorylated) [cytosol] (Gallus gallus)

Other forms of this molecule

phospho-GAB1 [cytosol]

GAB1 [cytosol]

Inferred From

p-Y627,Y659-GAB1 [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 627 (in Homo sapiens)

Coordinate

627

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 659 (in Homo sapiens)

Coordinate

659

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_040525961.1, XP_040556218.1

ENSEMBL

ENSGALP00010010341, ENSGALT00010018791, ENSGALG00010007898

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