Reactome | TAB2 [plasma membrane]

TAB2 [plasma membrane]

Stable Identifier

R-GGA-168116

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

TAB2, A0A8V0XYF8

Locations in the PathwayBrowser

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Immune System (Gallus gallus)

- Adaptive Immune System (Gallus gallus)
  - TCR signaling (Gallus gallus)
    - Downstream TCR signaling (Gallus gallus)
      - Activation of IKK complex (Gallus gallus)
        
        TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Gallus gallus)
        
        phosphorylated TAK1 bound to TAB2 [cytosol] (Gallus gallus)
        
        TAB2 [plasma membrane] (Gallus gallus)
      - Activation of TAK1-TAB2 complex (Gallus gallus)
        
        TAB2/TAK1 complex [cytosol] (Gallus gallus)
        
        TAB2 [plasma membrane] (Gallus gallus)
        
        TAK1/TAB2 complex bound to TRAF6/CBM complex [plasma membrane] (Gallus gallus)
        
        phosphorylated TAK1 bound to TAB2 [cytosol] (Gallus gallus)
        
        TAB2 [plasma membrane] (Gallus gallus)
- Innate Immune System (Gallus gallus)
  - Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Gallus gallus)
    - NOD1/2 Signaling Pathway (Gallus gallus)
      - TAK1 is activated (Gallus gallus)
        
        PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Gallus gallus)
        
        TAK1 complex [plasma membrane] (Gallus gallus)
        
        TAB2,TAB3 [plasma membrane] (Gallus gallus)
        
        TAB2 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0XYF8

Gene Names

TAB2

Reference Genes

BioGPS Gene:421622 TAB2

ENSEMBL:ENSGALG00010006524.1

Monarch:421622 TAB2

NCBI Gene:421622 TAB2

UCSC:A0A8V0XYF8 TAB2

Reference Transcript

Other Identifiers

421622

GO:0005737

GO:0006954

GO:0007249

GO:0007507

GO:0008270

GO:0032496

GO:0038061

GO:0038066

GO:0042742

GO:0043123

GO:0043124

GO:0048856

GO:0060090

GO:0070530

GO:0070534

GO:0098542

GT_A_87_P014036

GT_A_87_P022809

GT_A_87_P098726

GT_A_87_P124623

Gga.10217.1.S1_s_at

Gga.17529.1.S1_s_at

Gga.2586.1.S1_at

GgaAffx.23874.1.S1_s_at

Participates

as a component of

as a member of

TAB2,TAB3 [plasma membrane] (Gallus gallus)

Other forms of this molecule

TAB2 [nucleoplasm]

TAB2 [endosome membrane]

TAB2 [cytosol]

Inferred From

TAB2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_040553571.1, XP_040522261.1

ENSEMBL

ENSGALG00010006524, ENSGALT00010015502, ENSGALP00010009045

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