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TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
Stable Identifier
R-GGA-166172
Type
Complex
Species
Gallus gallus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Gallus gallus)
Auto-ubiquitination of TRAF3 (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Gallus gallus)
IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Gallus gallus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Gallus gallus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Gallus gallus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Gallus gallus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Gallus gallus)
IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 (Gallus gallus)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Gallus gallus)
IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-IKBKE:K63polyUb-TANK:K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
OPTN binds TBK1 within the activated TLR4 complex (Gallus gallus)
OPTN:TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [plasma membrane] (Gallus gallus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Gallus gallus)
K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TBK1 is phosphorylated within the activated TLR4 complex (Gallus gallus)
OPTN:TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [plasma membrane] (Gallus gallus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRAF3 binds TICAM1:activated TLR4 complex (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
IKK complex recruitment mediated by RIP1 (Gallus gallus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Gallus gallus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Gallus gallus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Gallus gallus)
Activated TLR4:TICAM1 recruits TRAF6 (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Gallus gallus)
K63-linked polyUb TRAF6 complexes [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Activation of TAK1 complex bound to activated TLR4 complex (Gallus gallus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Phosphorylated TAK1 leaves activated TLR receptor complex (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TRIF-mediated programmed cell death (Gallus gallus)
Caspase-8 processing within TLR4 complex (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TLR4-induced ripoptosome assembly (Gallus gallus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Gallus gallus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Gallus gallus)
K63-linked polyUb TRAF6 complexes [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Toll Like Receptor 9 (TLR9) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Gallus gallus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Gallus gallus)
K63-linked polyUb TRAF6 complexes [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
Programmed Cell Death (Gallus gallus)
Apoptosis (Gallus gallus)
Caspase activation via extrinsic apoptotic signalling pathway (Gallus gallus)
Caspase activation via Death Receptors in the presence of ligand (Gallus gallus)
Caspase-8 processing within TLR4 complex (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
TICAM1 [cytosol]
(Gallus gallus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Gallus gallus)
Participates
as an output of
Phosphorylated TAK1 leaves activated TLR receptor complex (Gallus gallus)
TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Gallus gallus)
as an input of
TRAF3 binds TICAM1:activated TLR4 complex (Gallus gallus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Gallus gallus)
Activated TLR4:TICAM1 recruits TRAF6 (Gallus gallus)
as a component of
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Gallus gallus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Gallus gallus)
TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Gallus gallus)
as a member of
TRIF:activated TLR4 [endosome membrane] (Gallus gallus)
Inferred From
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Homo sapiens)
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