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MLST8 [cytosol]
Stable Identifier
R-GGA-165676
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
MLST8, A0A8V0Z4H5
Locations in the PathwayBrowser
Expand all
Autophagy (Gallus gallus)
Macroautophagy (Gallus gallus)
Active MTORC1 binds the ULK1 complex (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Active MTORC1 phosphorylates ULK1 (Gallus gallus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
MTORC1 dissociates from ULK complex (Gallus gallus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Rheb in the MTORC1 complex hydrolyses GTP (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Gallus gallus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Cellular responses to stimuli (Gallus gallus)
Cellular responses to mechanical stimuli (Gallus gallus)
Response of endothelial cells to shear stress (Gallus gallus)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Gallus gallus)
mTORC2 phosphorylates AKT1 on serine-473 (Gallus gallus)
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to starvation (Gallus gallus)
Amino acids regulate mTORC1 (Gallus gallus)
RRAGA,B hydrolyzes GTP (Gallus gallus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Gallus gallus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
Regulation of TP53 Activity (Gallus gallus)
Regulation of TP53 Expression and Degradation (Gallus gallus)
Regulation of TP53 Degradation (Gallus gallus)
mTORC2 phosphorylates SGK1 (Gallus gallus)
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Regulation of T cell activation by CD28 family (Gallus gallus)
Co-stimulation by CD28 (Gallus gallus)
CD28 dependent PI3K/Akt signaling (Gallus gallus)
mTORC2 phosphorylates AKT at S473 (Gallus gallus)
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
PTEN Regulation (Gallus gallus)
Regulation of PTEN gene transcription (Gallus gallus)
MAF1 translocates to the nucleus (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1 phosphorylates MAF1 (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC2 phosphorylates AKT at S473 (Gallus gallus)
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC2 phosphorylates SGK1 (Gallus gallus)
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
MTOR signalling (Gallus gallus)
Energy dependent regulation of mTOR by LKB1-AMPK (Gallus gallus)
AMPK phosphorylates Raptor in the mTORC1 complex (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1-mediated signalling (Gallus gallus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Gallus gallus)
Active mTORC1 complex [lysosomal membrane] (Gallus gallus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated vascular permeability (Gallus gallus)
mTORC2 phosphorylates AKT at S473 (Gallus gallus)
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
MLST8 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A8V0Z4H5
Gene Names
MLST8
Reference Genes
BioGPS Gene:416558 MLST8
ENSEMBL:ENSGALG00010018075.1
Monarch:416558 MLST8
NCBI Gene:416558 MLST8
UCSC:A0A8V0Z4H5 MLST8
Reference Transcript
RefSeq:XM_040647890.2 MLST8
RefSeq:XM_040684006.2 MLST8
Other Identifiers
416558
GO:0005515
GO:0005737
GO:0005764
GO:0005765
GO:0016020
GO:0030674
GO:0030838
GO:0031929
GO:0031931
GO:0031932
GO:0032008
GO:0032956
GO:0038202
GO:0038203
GO:0043491
GO:0043539
GO:0051897
GO:0060090
GO:0098772
GO:1902554
GT_A_87_P003440
GT_A_87_P235743
GgaAffx.3670.1.S1_at
Participates
as a component of
mTORC2:PIP3 [plasma membrane] (Gallus gallus)
mTORC1 [cytosol] (Gallus gallus)
mTORC1 with p-S722,S792-RPTOR [cytosol] (Gallus gallus)
Other forms of this molecule
MLST8 [nucleoplasm]
Inferred From
MLST8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_040503824.1
,
XP_040539940.1
ENSEMBL
ENSGALP00010026008
,
ENSGALT00010043709
,
ENSGALG00010018075
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