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PPP2R5E [cytosol]
Stable Identifier
R-GGA-1638770
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
PPP2R5E, F1NLM6
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle Checkpoints (Gallus gallus)
Mitotic Spindle Checkpoint (Gallus gallus)
Amplification of signal from the kinetochores (Gallus gallus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Gallus gallus)
MAD2 associates with the Mad1 kinetochore complex (Gallus gallus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
Mad1:kinetochore complex [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Mad1:kinetochore complex [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Gallus gallus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
Mad1:kinetochore complex [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Mad1 binds kinetochore (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Mad1:kinetochore complex [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Release of activated MAD2 from kinetochores (Gallus gallus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
Mad1:kinetochore complex [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Mad1:kinetochore complex [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Metaphase and Anaphase (Gallus gallus)
Mitotic Anaphase (Gallus gallus)
Separation of Sister Chromatids (Gallus gallus)
ESPL1 (Separase) cleaves centromeric cohesin (Gallus gallus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Mitotic Prometaphase (Gallus gallus)
EML4 and NUDC in mitotic spindle formation (Gallus gallus)
EML4 recruits NUDC to mitotic spindle (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Resolution of Sister Chromatid Cohesion (Gallus gallus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Gallus gallus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Kinetochore assembly (Gallus gallus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
PP2A-B56 dephosphorylates centromeric cohesin (Gallus gallus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Phosphorylation of cohesin by PLK1 at centromeres (Gallus gallus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
Microtubule-bound kinetochore [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CTLA4 inhibitory signaling (Gallus gallus)
CTLA-4 binds B7-1/B7-2 (Gallus gallus)
CTLA4 dimer:PP2A [plasma membrane] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
PP2A:CTLA4:B7-1/B7-2 [plasma membrane] (Gallus gallus)
CTLA4 dimer:PP2A [plasma membrane] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate Formins (Gallus gallus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Gallus gallus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Gallus gallus)
Kinetochore [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Signaling by WNT (Gallus gallus)
Degradation of beta-catenin by the destruction complex (Gallus gallus)
AXIN is phosphorylated in the destruction complex (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Association of beta-catenin with the destruction complex (Gallus gallus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Beta-catenin phosphorylation cascade (Gallus gallus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Gallus gallus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Gallus gallus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Gallus gallus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
Phosphorylation of APC component of the destruction complex (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
PP2A [cytosol] (Gallus gallus)
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
PPP2R5E [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NLM6
Gene Names
PPP2R5E
Reference Genes
BioGPS Gene:423512 PPP2R5E
ENSEMBL:ENSGALG00000011840
ENSEMBL:ENSGALG00010017701.1 PPP2R5E
KEGG Gene (Gallus gallus):423512 PPP2R5E
Monarch:423512 PPP2R5E
NCBI Gene:423512 PPP2R5E
Reference Transcript
RefSeq:XM_015287891.1 PPP2R5E
RefSeq:XM_015287890.1 PPP2R5E
Other Identifiers
423512
GO:0000159
GO:0005634
GO:0005829
GO:0007165
GO:0019888
GO:0023052
GO:0043226
GO:0072542
GO:0098772
GT_A_87_P016447
Gga.16696.1.S1_at
GgaAffx.7523.1.S1_at
Participates
as a candidate of
PP2A regulatory subunit B56 [cytosol] (Gallus gallus)
Inferred From
PPP2R5E [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_015143376.1
,
XP_015143377.1
OpenTargets
ENSG00000154001
Ensembl
ENSGALT00010042797
,
ENSGALP00010025287
,
ENSGALG00010017701
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