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NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane]
Stable Identifier
R-GGA-1251957
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
PI3K:p-ERBB4cyt1 [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
PI3K:p-ERBB4cyt1 [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs [plasma membrane] (Gallus gallus)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ERBB4 (Gallus gallus)
PI3K events in ERBB4 signaling (Gallus gallus)
Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Gallus gallus)
PI3K:p-ERBB4cyt1 [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Gallus gallus)
PI3K:p-ERBB4cyt1 [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
SHC1 events in ERBB4 signaling (Gallus gallus)
Phosphorylation of SHC1 by ERBB4 homodimers (Gallus gallus)
SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Gallus gallus)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Gallus gallus)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
SHC1 binds P-ERBB4 isoform dimers (Gallus gallus)
SHC1:p-ERBB4 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
Trans-autophosphorylation of ERBB4 homodimers (Gallus gallus)
p-ERBB4 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4cyt1 homodimers [plasma membrane] (Gallus gallus)
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
NRGs/EGF-like ligands [extracellular region]
(Gallus gallus)
phospho-p-Y1056,Y1188,Y1242-ERBB4 JM-A CYT-1 isoform [plasma membrane]
(Gallus gallus)
Participates
as a component of
p-ERBB4jmAcyt1 [plasma membrane] (Gallus gallus)
Inferred From
NRGs/EGF-like ligands:P-ERBB4jmAcyt1 [plasma membrane]
(Homo sapiens)
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