Reactome | mhc1lla [lumenal side of endoplasmic reticulum membrane]

mhc1lla [lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-DRE-983073

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

lumenal side of endoplasmic reticulum membrane

Synonyms

class I MHC B7, A0A0G2KIH5

Locations in the PathwayBrowser

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Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - Class I MHC mediated antigen processing & presentation (Danio rerio)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Danio rerio)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - Budding of COPII coated vesicle (Danio rerio)
        
        COPII vesicle with MHC class I [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Danio rerio)
        
        MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC class I HC:Calnexin/BiP:Erp57 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - Loading of antigenic peptides on to class I MHC (Danio rerio)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Danio rerio)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Danio rerio)
        
        MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Danio rerio)
        
        MHC HC:B2M:Erp57 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Danio rerio)
        
        COPII vesicle with MHC class I [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - Transport of MHC heterotrimer to ER exit site (Danio rerio)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Peptide bound class I MHC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Class I MHC heavy chain (MHC HC) [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc1lla [lumenal side of endoplasmic reticulum membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0G2KIH5

Gene Names

mhc1lla

Reference Genes

BioGPS Gene:100536492 mhc1lla

CTD Gene:100536492 mhc1lla

ENSEMBL:ENSDARG00000096977

KEGG:dre:100536492 mhc1lla

Monarch:100536492 mhc1lla

NCBI Gene:100536492 mhc1lla

UCSC:A0A0G2KIH5 mhc1lla

Reference Transcript

Other Identifiers

100536492

DRER55257

Participates

as a member of

Homologues of class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)

Other forms of this molecule

mhc1lla [extracellular region]

mhc1lla [plasma membrane]

mhc1lla [extracellular region]

mhc1lla [plasma membrane]

mhc1lla [lumenal side of endoplasmic reticulum membrane]

mhc1lla [plasma membrane]

mhc1lla [azurophil granule membrane]

mhc1lla [secretory granule membrane]

mhc1lla [ER to Golgi transport vesicle membrane]

mhc1lla [Golgi membrane]

mhc1lla [plasma membrane]

mhc1lla [phagocytic vesicle membrane]

mhc1lla [recycling endosome membrane]

mhc1lla [early endosome membrane]

Inferred From

class I MHC B7 [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

HLA-H [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_073797760.1, NP_001314818.1, XP_073797759.1

ENSEMBL

ENSDARG00000096977, ENSDARP00000132118, ENSDART00000170929