Reactome | fi35c01 [cytosol]

fi35c01 [cytosol]

Stable Identifier

R-DRE-976024

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

SPSB1, Q4V8W1

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Danio rerio)

- Post-translational protein modification (Danio rerio)
  - Neddylation (Danio rerio)
    - AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Danio rerio)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
      - NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Danio rerio)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Danio rerio)
        
        CRL E3 ubiquitin ligases [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
      - CRL E3 ubiquitin ligases [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Danio rerio)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Danio rerio)
        
        CRL E3 ubiquitin ligases [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Danio rerio)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
    - NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Danio rerio)
      - CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
        
        CUL5-box protein [cytosol] (Danio rerio)
        
        fi35c01 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q4V8W1

Gene Names

fi35c01

Reference Genes

BioGPS Gene:334190 fi35c01

ENSEMBL:ENSDARG00000056515

ENSEMBL:ENSDARG00000056515.4 fi35c01

ENSEMBL:ENSDARG00000110015.1 fi35c01

KEGG Gene (Danio rerio):334190 fi35c01

Monarch:334190 fi35c01

NCBI Gene:334190 fi35c01

Reference Transcript

Other Identifiers

13139873

13282920

334190

A_15_P107913

CJ005304

CJ005305

DRER11319

Dr.7322.1.A1_at

ENSDART00000079019

ENSDART00000079019_1

ENSDART00000079019_2

GO:0005515

GO:0016567

GO:0019005

GO:0030163

GO:0036211

GO:0043161

JP005703

JP005704

LOLS12742

MADDr01003554

NM_001025460

ZV700S00006086

Participates

as a member of

Inferred From

SPSB1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001020631.1, XP_021325427.1

ZFIN

ZDB-GENE-030131-6122

Ensembl

ENSDARP00000073475, ENSDARP00000155648, ENSDART00000079019, ENSDART00000181785, ENSDARG00000056515, ENSDARG00000110015

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