Reactome | IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2

IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2

Stable Identifier

R-DRE-8987202

Type

Reaction [omitted]

Species

Danio rerio

Compartment

cytosol, extracellular region, plasma membrane

Synonyms

JAK1 and TYK2 are phosphorylated by IFNL1:IFNLR1:JAK1:IL10RB:TYK2 receptor complex, JAK1 and tyk2 are phosphorylated after il29-il29 receptor interaction

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IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2

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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

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