Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
spg7 [mitochondrial inner membrane]
Stable Identifier
R-DRE-8953712
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
mitochondrial inner membrane
Synonyms
SPG7, E7F2S4
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Danio rerio)
Mitochondrial protein degradation (Danio rerio)
AFG3L2:SPG7 binds SMDT1 (EMRE) (Danio rerio)
AFG3L2:SPG7:SMDT1 [mitochondrial inner membrane] (Danio rerio)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Danio rerio)
SPG7:Zn2+ [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Danio rerio)
SPG7:Zn2+ [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Danio rerio)
AFG3L2:SPG7:SMDT1 [mitochondrial inner membrane] (Danio rerio)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Danio rerio)
SPG7:Zn2+ [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Danio rerio)
SPG7:Zn2+ [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
SPG7:Zn2+ [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
Transport of small molecules (Danio rerio)
Mitochondrial calcium ion transport (Danio rerio)
Processing of SMDT1 (Danio rerio)
AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Danio rerio)
C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Danio rerio)
C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Danio rerio)
C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
proSMDT1:C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
spg7 [mitochondrial inner membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:E7F2S4
Gene Names
spg7
Reference Genes
BioGPS Gene:794740 spg7
ENSEMBL:ENSDARG00000068187
KEGG:dre:794740 spg7
Monarch:794740 spg7
NCBI Gene:794740 spg7
UCSC:E7F2S4 spg7
Reference Transcript
RefSeq:XM_001923083.7 spg7
Other Identifiers
13240543
794740
A_15_P119269
A_15_P144996
A_15_P213806
DRER14729
Dr.18511.1.A1_at
ENSDART00000031558_1
ENSDART00000031558_2
ENSDART00000098438
GO:0004176
GO:0004222
GO:0005524
GO:0006508
GO:0008270
GO:0016020
GO:0016787
GO:0016887
GO:0140657
GT_Spec_XM_001923083.3_70271
XM_684676
ZV700S00002897
Participates
as a component of
SPG7:Zn2+ [mitochondrial inner membrane] (Danio rerio)
C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] (Danio rerio)
Inferred From
SPG7 [mitochondrial inner membrane]
(Homo sapiens)
Cross References
RefSeq
XP_001923118.1
ENSEMBL
ENSDART00000098438
,
ENSDARG00000068187
,
ENSDARP00000089209
ZFIN
ZDB-GENE-030131-5391
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text