Reactome | snapc5 [nucleoplasm]

snapc5 [nucleoplasm]

Stable Identifier

R-DRE-83724

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

SNAPC5, Q1LXI0

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - RNA polymerase II transcribes snRNA genes (Danio rerio)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
    - General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Danio rerio)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
    - Integrator complex processes the 3' end of snRNA (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
    - RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Danio rerio)
      - Initiation factors:CDK7:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
    - SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Danio rerio)
      - SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
      - SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
- RNA Polymerase III Transcription (Danio rerio)
  - RNA Polymerase III Transcription Initiation (Danio rerio)
    - RNA Polymerase III Transcription Initiation From Type 3 Promoter (Danio rerio)
      - Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Danio rerio)
        
        RNA Polymerase III:TFIIIB:SNAPc:Type 3 Promoter Complex [nucleoplasm] (Danio rerio)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Danio rerio)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)
        
        TFIIIB:SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Danio rerio)
        
        SNAPc:Oct-1:Staf:Type 3 Promoter Complex [nucleoplasm] (Danio rerio)
        
        SNAPc [nucleoplasm] (Danio rerio)
        
        snapc5 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:Q1LXI0

Gene Names

snapc5

Reference Genes

BioGPS Gene:492409 snapc5

ENSEMBL:ENSDARG00000062476

KEGG:dre:492409 snapc5

Monarch:492409 snapc5

NCBI Gene:492409 snapc5

UCSC:Q1LXI0 snapc5

Reference Transcript

Other Identifiers

13063371

13283330

492409

A_15_P723046

DRER13761

ENSDART00000090413

ENSDART00000090413_1

GO:0005634

GO:0006351

GO:0006366

GO:0006384

NM_001080163

OTTDART00000021351

Participates

as a component of

SNAPc [nucleoplasm] (Danio rerio)

Inferred From

SNAPC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_005159142.1, NP_001073632.1

ENSEMBL

ENSDART00000090413, ENSDARP00000084846, ENSDARG00000062476

ZFIN

ZDB-GENE-041111-50

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