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phospho-polr2a [nucleoplasm]
Stable Identifier
R-DRE-77100
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
nucleoplasm
Synonyms
p-S5(CTD)-POLR2A, A0A0R4IMS9
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
RNA Pol II CTD phosphorylation and interaction with CE (Danio rerio)
Activation of GT (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Phosphorylation (Ser5) of RNA pol II CTD (Danio rerio)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Polymerase II CTD (phosphorylated) binds to CE (Danio rerio)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Polymerase II Pre-transcription Events (Danio rerio)
Abortive termination of early transcription elongation by DSIF:NELF (Danio rerio)
DSIF:NELF:early elongation complex [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Polymerase II Transcription Elongation (Danio rerio)
Formation of the Early Elongation Complex (Danio rerio)
DSIF complex binds to RNA Pol II (hypophosphorylated) (Danio rerio)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Formation of DSIF:NELF:early elongation complex (Danio rerio)
DSIF:NELF:early elongation complex [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Danio rerio)
RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Danio rerio)
RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] (Danio rerio)
RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Metabolism of RNA (Danio rerio)
Processing of Capped Intron-Containing Pre-mRNA (Danio rerio)
Internal Methylation of mRNA (Danio rerio)
capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] (Danio rerio)
RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
mRNA Capping (Danio rerio)
Activation of GT (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Capping complex formation (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Capping complex (initial) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Dissociation of transcript with 5'-GMP from GT (Danio rerio)
Capping complex (GpppN..) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Formation of the CE:GMP intermediate complex (Danio rerio)
Capping complex (intermediate) [nucleoplasm] (Danio rerio)
Covalent CE:GMP intermediate complex [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Capping complex (hydrolyzed) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Danio rerio)
Capping complex (hydrolyzed) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Capping complex (initial) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Methylation of GMP-cap by RNA Methyltransferase (Danio rerio)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Polymerase II CTD (phosphorylated) binds to CE (Danio rerio)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Danio rerio)
Capping complex (intermediate) [nucleoplasm] (Danio rerio)
Covalent CE:GMP intermediate complex [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Capping complex (GpppN..) [nucleoplasm] (Danio rerio)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Danio rerio)
RNA polymerase II (phosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Estrogen-dependent gene expression (Danio rerio)
p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Danio rerio)
MYB gene:hypophosphorylated RNA polymerase II:TFIIF:ESR1:ESTG:P-TEFb [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
phospho-polr2a [nucleoplasm] (Danio rerio)
External Reference Information
External Reference
UniProt:A0A0R4IMS9
Gene Names
polr2a
Reference Genes
BioGPS Gene:553347 polr2a
ENSEMBL:ENSDARG00000099966
KEGG:dre:553347 polr2a
Monarch:553347 polr2a
NCBI Gene:553347 polr2a
UCSC:A0A0R4IMS9 polr2a
Reference Transcript
RefSeq:XM_005156225.5 polr2a
Other Identifiers
12985396
13286708
553347
A_15_P134436
A_15_P166656
CJ006917
CJ006918
CJ007587
CJ007588
CJ007915
CJ007916
CJ008041
CJ008042
CJ008694
CJ008695
CJ009691
CJ009692
CJ010310
CJ010311
CUST_2002_PI423953333
CUST_2003_PI423953333
CUST_2004_PI423953333
CUST_2005_PI423953333
CUST_2006_PI423953333
CUST_2007_PI423953333
CUST_2008_PI423953333
CUST_5033_PI423953333
CUST_5034_PI423953333
CUST_5037_PI423953333
CUST_5038_PI423953333
CUST_5743_PI428451958
CUST_8879_PI428451953
DRER10858
Dr.15833.1.A1_at
Dr.15833.2.S1_at
ENSDART00000077495
ENSDART00000077495_1
GO:0003677
GO:0003824
GO:0003899
GO:0006351
GO:0006366
GO:0016740
GO:0140098
GT_Xhyb_XM_005156225.1_368655
GT_Xhyb_XM_677590.3_368665
JP007315
JP007316
JP007985
JP007986
JP008313
JP008314
JP008439
JP008440
JP009092
JP009093
JP010089
JP010090
JP010708
JP010709
LOLS05144
LOLS10071
TC238569
XM_677590
XM_681282
ZV700S00001917
ZV700S00001918
Participates
as a component of
RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Danio rerio)
RNA Polymerase II holoenzyme complex (phosphorylated) [nucleoplasm] (Danio rerio)
Other forms of this molecule
phospho-polr2a [nucleoplasm]
phospho-polr2a [nucleoplasm]
phospho-polr2a [nucleoplasm]
phospho-polr2a [nucleoplasm]
phospho-polr2a [nucleoplasm]
phospho-polr2a [nucleoplasm]
polr2a [nucleoplasm]
Inferred From
p-S5(CTD)-POLR2A [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1843 (in Homo sapiens)
Coordinate
1843
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1850 (in Homo sapiens)
Coordinate
1850
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1857 (in Homo sapiens)
Coordinate
1857
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1864 (in Homo sapiens)
Coordinate
1864
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1871 (in Homo sapiens)
Coordinate
1871
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1878 (in Homo sapiens)
Coordinate
1878
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1892 (in Homo sapiens)
Coordinate
1892
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1899 (in Homo sapiens)
Coordinate
1899
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1906 (in Homo sapiens)
Coordinate
1906
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1913 (in Homo sapiens)
Coordinate
1913
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1920 (in Homo sapiens)
Coordinate
1920
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1927 (in Homo sapiens)
Coordinate
1927
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1934 (in Homo sapiens)
Coordinate
1934
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_005156282.1
ENSEMBL
ENSDARP00000135038
,
ENSDART00000172066
,
ENSDARG00000099966
ZFIN
ZDB-GENE-041008-78
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