Reactome | rpl10 [cytosol]

rpl10 [cytosol]

Stable Identifier

R-DRE-72402

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

RPL10, Q7ZV96

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Danio rerio)

- Nonsense-Mediated Decay (NMD) (Danio rerio)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Danio rerio)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
    - SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Danio rerio)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Danio rerio)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Danio rerio)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Danio rerio)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Danio rerio)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
        
        80S ribosome [cytosol] (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)
- rRNA processing (Danio rerio)
  - rRNA processing in the nucleus and cytosol (Danio rerio)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Danio rerio)
      - 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Danio rerio)
        
        60S ribosomal complex [cytosol] (Danio rerio)
        
        rpl10 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7ZV96

Gene Names

rpl10

Reference Genes

BioGPS Gene:336712 rpl10

ENSEMBL:ENSDARG00000025581

Monarch:336712 rpl10

NCBI Gene:336712 rpl10

UCSC:Q7ZV96 rpl10

Reference Transcript

Other Identifiers

12922839

12922841

12922843

12922845

12926303

12926305

12926307

12926309

12934079

12934081

12934083

12934085

13139365

336712

A_15_P173111

A_15_P486825

A_15_P548847

A_15_P661171

A_15_P721766

CUST_13054_PI428451953

CUST_13055_PI428451953

CUST_13056_PI428451953

DRER04057

DRER21398

DRER21758

DRER31552

DRER38608

DRER40677

DRER40774

DRER42316

DRER43852

DRER45485

Dr.1329.1.S1_at

ENSDART00000032744

ENSDART00000032744_1

ENSDART00000032744_2

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GT_Xhyb_NM_200027.1_229065

GT_Xhyb_XM_005162041.1_410555

GT_Xhyb_XM_005162042.1_184025

MADDr01001620

NM_200027

ZV700S00000984

Participates

as a component of

Other forms of this molecule

rpl10 [cytosol]

Inferred From

RPL10,RPL10L [cytosol] (Homo sapiens)

RPL10 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_073794220.1, NP_956321.1

ENSEMBL

ENSDART00000182714, ENSDARP00000120909, ENSDART00000131860, ENSDART00000032744, ENSDARP00000036951, ENSDARP00000149077, ENSDARG00000117015, ENSDARG00000115128, ENSDARP00000119262, ENSDART00000192800, ENSDARP00000145934, ENSDART00000142072, ENSDARG00000025581

ZFIN

ZDB-GENE-030131-8656

PRO

Q7ZV96

PDB

7OYB, 7OYA

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