Reactome | sf3b2 [nucleoplasm]

sf3b2 [nucleoplasm]

Stable Identifier

R-DRE-71971

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

SF3B2, A7YT51

Locations in the PathwayBrowser

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Metabolism of RNA (Danio rerio)

- Processing of Capped Intron-Containing Pre-mRNA (Danio rerio)
  - mRNA 3'-end processing (Danio rerio)
    - mRNA Polyadenylation (Danio rerio)
      - Core CPA complex binds capped pre-mRNA (Danio rerio)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Danio rerio)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Danio rerio)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Danio rerio)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - PP1 dephosphorylates RNA Pol II (Danio rerio)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - RBBP6 activates CPSF complex (Danio rerio)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Danio rerio)
        
        U2 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
  - mRNA Splicing (Danio rerio)
    - mRNA Splicing - Minor Pathway (Danio rerio)
      - ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Danio rerio)
        
        ATAC C Complex [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Danio rerio)
        
        ATAC C Complex [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - Formation of AT-AC B Complex (Danio rerio)
        
        ATAC A Complex [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        ATAC B Complex [nucleoplasm] (Danio rerio)
        
        ATAC A Complex [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
      - Formation of AT-AC C complex (Danio rerio)
        
        ATAC B Complex [nucleoplasm] (Danio rerio)
        
        ATAC A Complex [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)
        
        ATAC C Complex [nucleoplasm] (Danio rerio)
        
        U12 snRNP [nucleoplasm] (Danio rerio)
        
        SF3B [nucleoplasm] (Danio rerio)
        
        sf3b2 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:A7YT51

Gene Names

sf3b2

Reference Genes

BioGPS Gene:570994 sf3b2

ENSEMBL:ENSDARG00000018049

KEGG:dre:570994 sf3b2

Monarch:570994 sf3b2

NCBI Gene:570994 sf3b2

UCSC:A7YT51 sf3b2

Reference Transcript

RefSeq:NM_001105277.3 sf3b2

Other Identifiers

13225522

570994

A_15_P106274

A_15_P143741

CUST_153_PI424165052

CUST_154_PI424165052

CUST_155_PI424165052

CUST_156_PI424165052

CUST_157_PI424165052

CUST_158_PI424165052

CUST_159_PI424165052

CUST_160_PI424165052

CUST_6029_PI428451953

DRER01922

Dr.5469.1.A1_at

ENSDART00000015873

ENSDART00000015873_1

ENSDART00000015873_2

GO:0005634

GT_Spec_NM_001105277.1_204145

LOLS02192

TC260685

XM_691025

XM_694544

ZV700S00005626

Participates

as a component of

SF3B [nucleoplasm] (Danio rerio)

Inferred From

SF3B2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001098747.1

ENSEMBL

ENSDARG00000018049, ENSDARP00000007002, ENSDART00000015873

ZFIN

ZDB-GENE-070928-1

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