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26S proteasome [cytosol]
Stable Identifier
R-DRE-68819
Type
Complex
Species
Danio rerio
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
G1/S DNA Damage Checkpoints (Danio rerio)
p53-Dependent G1/S DNA damage checkpoint (Danio rerio)
p53-Dependent G1 DNA Damage Response (Danio rerio)
Stabilization of p53 (Danio rerio)
Autodegradation of the E3 ubiquitin ligase COP1 (Danio rerio)
Proteasome mediated degradation of COP1 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
G2/M Checkpoints (Danio rerio)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G2-G2/M phases (Danio rerio)
G2/M Transition (Danio rerio)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Danio rerio)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Proteasome-mediated degradation of PolyUb-FBXL7 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
The role of GTSE1 in G2/M progression after G2 checkpoint (Danio rerio)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
S Phase (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Ubiquitin-dependent degradation of Cyclin D (Danio rerio)
Proteasome mediated degradation of Cyclin D1 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
KEAP1-NFE2L2 pathway (Danio rerio)
26S proteasome degrades Ub-NFE2L2 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
ub UBXN7 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
DNA Replication (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional regulation by RUNX1 (Danio rerio)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Danio rerio)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen processing-Cross presentation (Danio rerio)
Cross-presentation of soluble exogenous antigens (endosomes) (Danio rerio)
Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
Proteasomal cleavage of substrate (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of NF-kappaB in B cells (Danio rerio)
Ubiquitinated IkB is degraded (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of polyamines (Danio rerio)
Regulation of ornithine decarboxylase (ODC) (Danio rerio)
26S proteosome degrades ODC holoenzyme complex (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Metabolism of RNA (Danio rerio)
Regulation of mRNA stability by proteins that bind AU-rich elements (Danio rerio)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Danio rerio)
AUF1:mRNA complex is destroyed (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
UCH proteinases (Danio rerio)
ADRM1 binds 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
ADRM1:26S proteaseome binds UCHL5 (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
ADRM1:26S proteasome:UCHL5 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Ub-specific processing proteases (Danio rerio)
ADRM1:26S proteaseome binds USP14 (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
ADRM1:26S proteasome:USP14 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Neddylation (Danio rerio)
26S proteasome degrades HIFalpha (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
26S proteasome degrades Ub-NFE2L2 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
ub UBXN7 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
PTEN Regulation (Danio rerio)
Regulation of PTEN stability and activity (Danio rerio)
Proteasome degrades polyubiquitinated PTEN (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK6/MAPK4 signaling (Danio rerio)
MAPK6 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Signaling by Hedgehog (Danio rerio)
Hedgehog 'off' state (Danio rerio)
Degradation of GLI1 by the proteasome (Danio rerio)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
GLI3 is processed to GLI3R by the proteasome (Danio rerio)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Hedgehog ligand biogenesis (Danio rerio)
Hh C-terminal fragments are degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Signaling by WNT (Danio rerio)
Beta-catenin independent WNT signaling (Danio rerio)
PCP/CE pathway (Danio rerio)
Asymmetric localization of PCP proteins (Danio rerio)
PRICKLE1 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
TCF dependent signaling in response to WNT (Danio rerio)
Degradation of AXIN (Danio rerio)
Ubiquitinated AXIN is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Degradation of DVL (Danio rerio)
Ubiquitinated DVL is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
misfolded CFTR is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
19S regulatory particle [cytosol]
(Danio rerio)
20S core particle [cytosol]
(Danio rerio)
Participates
as an input of
ADRM1 binds 26S proteasome (Danio rerio)
as a component of
ADRM1:26S proteasome [cytosol] (Danio rerio)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Danio rerio)
Inferred From
26S proteasome [cytosol]
(Homo sapiens)
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