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wu:fj14c10 [cytosol]
Stable Identifier
R-DRE-68768
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
PSMC1, Q6IQ72
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
G1/S DNA Damage Checkpoints (Danio rerio)
p53-Dependent G1/S DNA damage checkpoint (Danio rerio)
p53-Dependent G1 DNA Damage Response (Danio rerio)
Stabilization of p53 (Danio rerio)
Autodegradation of the E3 ubiquitin ligase COP1 (Danio rerio)
Proteasome mediated degradation of COP1 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
G2/M Checkpoints (Danio rerio)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G2-G2/M phases (Danio rerio)
G2/M Transition (Danio rerio)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Danio rerio)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Proteasome-mediated degradation of PolyUb-FBXL7 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
The role of GTSE1 in G2/M progression after G2 checkpoint (Danio rerio)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
S Phase (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Ubiquitin-dependent degradation of Cyclin D (Danio rerio)
Proteasome mediated degradation of Cyclin D1 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
KEAP1-NFE2L2 pathway (Danio rerio)
26S proteasome degrades Ub-NFE2L2 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
ub UBXN7 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
DNA Replication (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Ubiquitinated Cdc6 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional regulation by RUNX1 (Danio rerio)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Danio rerio)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen processing-Cross presentation (Danio rerio)
Cross-presentation of soluble exogenous antigens (endosomes) (Danio rerio)
Proteasomal clevage of exogenous antigen (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
Proteasomal cleavage of substrate (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of NF-kappaB in B cells (Danio rerio)
Ubiquitinated IkB is degraded (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of polyamines (Danio rerio)
Regulation of ornithine decarboxylase (ODC) (Danio rerio)
26S proteosome degrades ODC holoenzyme complex (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Metabolism of RNA (Danio rerio)
Regulation of mRNA stability by proteins that bind AU-rich elements (Danio rerio)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Danio rerio)
AUF1:mRNA complex is destroyed (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Danio rerio)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Danio rerio)
Deglycosylation complex [endoplasmic reticulum membrane] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Deubiquitination (Danio rerio)
UCH proteinases (Danio rerio)
ADRM1 binds 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
ADRM1:26S proteaseome binds UCHL5 (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
ADRM1:26S proteasome:UCHL5 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Ub-specific processing proteases (Danio rerio)
ADRM1:26S proteaseome binds USP14 (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
ADRM1:26S proteasome:USP14 [cytosol] (Danio rerio)
ADRM1:26S proteasome [cytosol] (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Neddylation (Danio rerio)
26S proteasome degrades HIFalpha (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
26S proteasome degrades Ub-NFE2L2 (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
ub UBXN7 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
PTEN Regulation (Danio rerio)
Regulation of PTEN stability and activity (Danio rerio)
Proteasome degrades polyubiquitinated PTEN (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK6/MAPK4 signaling (Danio rerio)
MAPK6 is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Signaling by Hedgehog (Danio rerio)
Hedgehog 'off' state (Danio rerio)
Degradation of GLI1 by the proteasome (Danio rerio)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
GLI3 is processed to GLI3R by the proteasome (Danio rerio)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Hedgehog ligand biogenesis (Danio rerio)
Hh C-terminal fragments are degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Signaling by WNT (Danio rerio)
Beta-catenin independent WNT signaling (Danio rerio)
PCP/CE pathway (Danio rerio)
Asymmetric localization of PCP proteins (Danio rerio)
PRICKLE1 is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
TCF dependent signaling in response to WNT (Danio rerio)
Degradation of AXIN (Danio rerio)
Ubiquitinated AXIN is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Degradation of DVL (Danio rerio)
Ubiquitinated DVL is degraded by the proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
misfolded CFTR is degraded by the 26S proteasome (Danio rerio)
26S proteasome [cytosol] (Danio rerio)
Homologues of PSMC1 [cytosol] (Danio rerio)
wu:fj14c10 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6IQ72
Gene Names
wu:fj14c10
Reference Genes
BioGPS Gene:415181 wu:fj14c10
CTD Gene:415181 wu:fj14c10
ENSEMBL:ENSDARG00000043561
ENSEMBL:ENSDARG00000043561.8 wu:fj14c10
KEGG Gene (Danio rerio):415181 wu:fj14c10
Monarch:415181 wu:fj14c10
NCBI Gene:415181 wu:fj14c10
Reference Transcript
RefSeq:NM_001002091.1 wu:fj14c10
Other Identifiers
13095020
415181
A_15_P100455
A_15_P112999
CUST_166_PI428451958
DRER08919
Dr.1187.1.A1_at
Dr.25360.1.A1_s_at
ENSDART00000063950
ENSDART00000063950_1
ENSDART00000063950_2
ENSDART00000103419
GO:0000166
GO:0000502
GO:0003824
GO:0005524
GO:0005737
GO:0008540
GO:0016787
GO:0016887
GO:0030163
GO:0036402
GO:0043161
GO:0140657
GO:1901800
GT_Spec_NM_001002091.1_351845
MADDr01005167
NM_001002091
OTTDART00000005013
Participates
as a member of
Homologues of PSMC1 [cytosol] (Danio rerio)
Other forms of this molecule
wu:fj14c10 [nucleoplasm]
Inferred From
PSMC1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001002091.1
ZFIN
ZDB-GENE-040625-69
Ensembl
ENSDARG00000043561
,
ENSDART00000063950
,
ENSDARP00000063949
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