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cdc6 [nucleoplasm]
Stable Identifier
R-DRE-68542
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
nucleoplasm
Synonyms
CDC6, A8KC19
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G1 phase and G1/S transition (Danio rerio)
G1/S Transition (Danio rerio)
Activation of the pre-replicative complex (Danio rerio)
CDK and DDK associate with the Mcm10:pre-replicative complex (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Cdc45 associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Cdt1 is displaced from the pre-replicative complex (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA polymerase alpha:primase binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA polymerase epsilon binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
S Phase (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Cdc6 protein is phosphorylated by CDK (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Orc1 removal from chromatin (Danio rerio)
Orc1 is phosphorylated by cyclin A/CDK2 (Danio rerio)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA Replication (Danio rerio)
DNA Replication Pre-Initiation (Danio rerio)
Activation of the pre-replicative complex (Danio rerio)
CDK and DDK associate with the Mcm10:pre-replicative complex (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Cdc45 associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Cdt1 is displaced from the pre-replicative complex (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA polymerase alpha:primase binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
DNA polymerase epsilon binds at the origin (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Danio rerio)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
MCM10:active pre-replicative complex [nucleoplasm] (Danio rerio)
active pre-replicative complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Danio rerio)
MCM10:pre-replicative complex [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Assembly of the pre-replicative complex (Danio rerio)
CDC6 association with the ORC:origin complex (Danio rerio)
CDC6 association with ORC(1-6) at replication origins (Danio rerio)
CDC6:MCM8 [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
MCM8 binds CDC6 (Danio rerio)
CDC6:MCM8 [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Cdc6 protein is phosphorylated by CDK (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
Orc1 removal from chromatin (Danio rerio)
Orc1 is phosphorylated by cyclin A/CDK2 (Danio rerio)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
pre-replicative complex [nucleoplasm] (Danio rerio)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
cdc6 [nucleoplasm] (Danio rerio)
External Reference Information
External Reference
UniProt:A8KC19
Gene Names
cdc6
Reference Genes
BioGPS Gene:402825 cdc6
ENSEMBL:ENSDARG00000009942
KEGG:dre:402825 cdc6
Monarch:402825 cdc6
NCBI Gene:402825 cdc6
UCSC:A8KC19 cdc6
Reference Transcript
RefSeq:NM_001127333.1 cdc6
Participates
as an input of
Cdc6 protein is phosphorylated by CDK (Danio rerio)
CDC6 association with ORC(1-6) at replication origins (Danio rerio)
MCM8 binds CDC6 (Danio rerio)
as a component of
pre-replicative complex (Orc1-minus) [nucleoplasm] (Danio rerio)
CDC6:MCM8 [nucleoplasm] (Danio rerio)
ORC(1-6):CDC6:origin of replication [nucleoplasm] (Danio rerio)
CDC6:ORC:origin complex [nucleoplasm] (Danio rerio)
Other forms of this molecule
cdc6 [cytosol]
phospho-cdc6 [cytosol]
phospho-cdc6 [nucleoplasm]
Inferred From
CDC6 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001120805.1
ZFIN
ZDB-GENE-050506-131
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