Reactome | tmed3 [transport vesicle]

tmed3 [transport vesicle]

Stable Identifier

R-DRE-6808874

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

transport vesicle

Synonyms

TMED3, B3DKM3

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Danio rerio)

- Post-translational protein modification (Danio rerio)
  - Asparagine N-linked glycosylation (Danio rerio)
    - Transport to the Golgi and subsequent modification (Danio rerio)
      - ER to Golgi Anterograde Transport (Danio rerio)
        
        COPI-mediated anterograde transport (Danio rerio)
        
        ARFGAPs stimulate ARF GTPase activity (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Danio rerio)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Danio rerio)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)

Vesicle-mediated transport (Danio rerio)

- Membrane Trafficking (Danio rerio)
  - ER to Golgi Anterograde Transport (Danio rerio)
    - COPI-mediated anterograde transport (Danio rerio)
      - ARFGAPs stimulate ARF GTPase activity (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Danio rerio)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Danio rerio)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Danio rerio)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Danio rerio)
    - Golgi-to-ER retrograde transport (Danio rerio)
      - COPI-dependent Golgi-to-ER retrograde traffic (Danio rerio)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Danio rerio)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Danio rerio)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Danio rerio)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Danio rerio)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Danio rerio)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo [transport vesicle] (Danio rerio)
        
        p24 dimers [transport vesicle] (Danio rerio)
        
        TMED3 dimer [transport vesicle] (Danio rerio)
        
        tmed3 [transport vesicle] (Danio rerio)

External Reference Information

External Reference

UniProt:B3DKM3

Gene Names

tmed3

Reference Genes

BioGPS Gene:336391 tmed3

ENSEMBL:ENSDARG00000028816

ENSEMBL:ENSDARG00000113132 tmed3

KEGG Gene (Danio rerio):336391 tmed3

Monarch:336391 tmed3

NCBI Gene:336391 tmed3

Reference Transcript

RefSeq:NM_001128668.1 tmed3

Other Identifiers

13237336

336391

A_15_P114426

A_15_P397605

BC056540.1

CUST_4618_PI428451958

DRER05678

Dr.4767.1.A1_a_at

Dr.4767.2.A1_at

Dr.4767.2.A1_x_at

ENSDART00000046689

ENSDART00000046689_1

ENSDART00000046689_2

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005793

GO:0005794

GO:0006810

GO:0006886

GO:0006888

GO:0007030

GO:0008150

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0030126

GO:0030134

GO:0031410

GO:0032991

GO:0033116

GO:0043226

GT_Spec_NM_001128668.1_372595

MADDr01007660

OTTDART00000025115

XM_693417

Participant Of

hasComponent

TMED3 dimer [transport vesicle]

Other forms of this molecule

tmed3 [endoplasmic reticulum membrane]

tmed3 [endoplasmic reticulum-Golgi intermediate compartment membrane]

tmed3 [Golgi membrane]

Inferred From

TMED3 [transport vesicle] (Homo sapiens)

Cross References

RefSeq

NP_001122140.1

Ensembl

ENSDARG00000113132, ENSDARG00000028816, ENSDART00000046689, ENSDART00000190210, ENSDARP00000149452, ENSDARP00000046688

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