Reactome | thbs1b [extracellular region]

thbs1b [extracellular region]

Stable Identifier

R-DRE-66518

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

extracellular region

Synonyms

THBS1, F1QL35

Locations in the PathwayBrowser

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Hemostasis (Danio rerio)

- Platelet activation, signaling and aggregation (Danio rerio)
  - Response to elevated platelet cytosolic Ca2+ (Danio rerio)
    - Platelet degranulation (Danio rerio)
      - Exocytosis of platelet alpha granule contents (Danio rerio)
        
        Platelet alpha granule contents [extracellular region] (Danio rerio)
        
        THBS1 trimer [extracellular region] (Danio rerio)
        
        thbs1b [extracellular region] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by PDGF (Danio rerio)
    - PDGF binds to extracellular matrix proteins (Danio rerio)
      - Extracellular matrix ligands [extracellular region] (Danio rerio)
        
        Thrombospondin [extracellular region] (Danio rerio)
        
        thbs1b [extracellular region] (Danio rerio)
      - PDGF A and B chains:ECM complex [extracellular region] (Danio rerio)
        
        Extracellular matrix ligands [extracellular region] (Danio rerio)
        
        Thrombospondin [extracellular region] (Danio rerio)
        
        thbs1b [extracellular region] (Danio rerio)

External Reference Information

External Reference

UniProt:F1QL35

Gene Names

thbs1b

Reference Genes

BioGPS Gene:561901 thbs1b

CTD Gene:561901 thbs1b

ENSEMBL:ENSDARG00000010785

KEGG:dre:561901 thbs1b

Monarch:561901 thbs1b

NCBI Gene:561901 thbs1b

UCSC:F1QL35 thbs1b

Reference Transcript

RefSeq:XM_005160762.5 thbs1b

Other Identifiers

13103409

561901

A_15_P184451

A_15_P368605

A_15_P518192

A_15_P533837

CJ013957

CJ014275

CUST_12508_PI428451958

CUST_18715_PI428451953

CUST_18716_PI428451953

DRER02084

DRER39209

DRER51084

Dr.2712.1.A1_at

ENSDART00000017090

ENSDART00000017090_1

ENSDART00000017090_2

GO:0005509

GO:0005515

GO:0005576

GO:0007155

GT_Xhyb_XM_005160762.1_424265

GT_Xhyb_XM_685303.6_424255

MADDr01004684

OTTDART00000006099

TC250077

XM_685303

Participates

as a member of

Thrombospondin [extracellular region] (Danio rerio)

as an input of

Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Danio rerio)

as a component of

Other forms of this molecule

thbs1b [endoplasmic reticulum lumen]

thbs1b [platelet alpha granule lumen]

Inferred From

THBS1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_005160819.1

ENSEMBL

ENSDARP00000120705, ENSDART00000140350, ENSDARG00000010785

ZFIN

ZDB-GENE-020708-1

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