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apc [cytosol]
Stable Identifier
R-DRE-5246690
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
K63polyUb-APC, A0A0R4IWH7
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
Ovarian tumor domain proteases (Danio rerio)
ZRANB1 binds APC (Danio rerio)
ZRANB1:K63polyUb-APC [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by WNT (Danio rerio)
Degradation of beta-catenin by the destruction complex (Danio rerio)
AXIN is phosphorylated in the destruction complex (Danio rerio)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Association of beta-catenin with the destruction complex (Danio rerio)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Beta-catenin phosphorylation cascade (Danio rerio)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Danio rerio)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Danio rerio)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Danio rerio)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Danio rerio)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
Phosphorylation of APC component of the destruction complex (Danio rerio)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
ZRANB1 binds APC (Danio rerio)
ZRANB1:K63polyUb-APC [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
apc [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:A0A0R4IWH7
Gene Names
apc
Reference Genes
BioGPS Gene:386762 apc
ENSEMBL:ENSDARG00000058868
KEGG:dre:386762 apc
Monarch:386762 apc
NCBI Gene:386762 apc
UCSC:A0A0R4IWH7 apc
Reference Transcript
RefSeq:NM_001143840.1 apc
Other Identifiers
12960180
386762
A_15_P157406
A_15_P344795
A_15_P473645
A_15_P597377
CJ003507
CUST_5093_PI428451953
CUST_5094_PI428451953
DRER05390
DRER47999
Dr.19924.1.A1_at
ENSDART00000044432
ENSDART00000044432_1
ENSDART00000044432_2
GO:0005515
GO:0008013
GO:0008017
GO:0008092
GO:0016055
GO:0030178
GT_Xhyb_NM_001143840.1_122416
GT_Xhyb_XM_005155522.1_278905
GT_Xhyb_XM_005155523.1_278915
JP003906
LOLG175
LOLG176
LOLG177
LOLS15232
TC254189
XM_690216
XM_690289
XM_696214
Participates
as an input of
ZRANB1 binds APC (Danio rerio)
as a component of
ZRANB1:K63polyUb-APC [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
Other forms of this molecule
apc [nucleoplasm]
phospho-apc [cytosol]
apc [cytosol]
apc [cytosol]
apc [cytosol]
Inferred From
K63polyUb-APC [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at unknown position
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_001137312.1
ENSEMBL
ENSDARG00000058868
,
ENSDARP00000139275
,
ENSDART00000158897
ZFIN
ZDB-GENE-031112-7
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