Reactome | casp10 [cytosol]

casp10 [cytosol]

Stable Identifier

R-DRE-51925-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

CFLAR(1-376), E7EXV8

Locations in the PathwayBrowser

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Programmed Cell Death (Danio rerio)

- Apoptosis (Danio rerio)
  - Caspase activation via extrinsic apoptotic signalling pathway (Danio rerio)
    - Caspase activation via Death Receptors in the presence of ligand (Danio rerio)
      - Regulation by c-FLIP (Danio rerio)
        
        Caspase-8 and FLIP(L) processing at DISC (Danio rerio)
        
        DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Danio rerio)
        
        Homologues of CFLAR(1-376) [cytosol] (Danio rerio)
        
        casp10 [cytosol] (Danio rerio)
- Regulated Necrosis (Danio rerio)
  - RIPK1-mediated regulated necrosis (Danio rerio)
    - Regulation of necroptotic cell death (Danio rerio)
      - CASP8 activity is inhibited (Danio rerio)
        
        FLIP(L) and procaspase-8 form heterodimer (Danio rerio)
        
        Homologues of CFLAR(1-376) [cytosol] (Danio rerio)
        
        casp10 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:E7EXV8

Gene Names

casp10

Reference Genes

BioGPS Gene:557302 casp10

ENSEMBL:ENSDARG00000070272

KEGG:dre:557302 casp10

Monarch:557302 casp10

NCBI Gene:557302 casp10

UCSC:E7EXV8 casp10

Reference Transcript

RefSeq:XM_680338.10 casp10

Other Identifiers

13257444

13281128

13284510

13285572

557302

A_15_P201106

A_15_P201111

CJ000093

CUST_3437_PI428451958

CUST_8019_PI428451953

CUST_8020_PI428451953

CUST_8021_PI428451953

DRER12344

DRER44357

ENSDART00000014766

ENSDART00000014766_1

ENSDART00000014766_2

ENSDART00000082478

ENSDART00000082478_1

ENSDART00000082478_2

GO:0004197

GO:0005515

GO:0006508

GO:0008234

GO:0042981

GT_Spec_XM_680338.6_230917

JP000093

MADDr01001211

XM_680338

Participates

as a member of

Homologues of CFLAR(1-376) [cytosol] (Danio rerio)

Other forms of this molecule

casp10 [cytosol]

casp10 [mitochondrial outer membrane]

casp10 [cytosol]

Inferred From

CFLAR(1-376) [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_685430.4

ENSEMBL

ENSDARP00000156873, ENSDART00000014766, ENSDARG00000070272, ENSDARP00000024255, ENSDART00000191361

ZFIN

ZDB-GENE-070608-2

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