Reactome | crfb12 [plasma membrane]

crfb12 [plasma membrane]

Stable Identifier

R-DRE-449841-9

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

IL10RA, Q1RM05

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - Signaling by Interleukins (Danio rerio)
    - Interleukin-10 signaling (Danio rerio)
      - IL10 dimer binds IL10RA:JAK1 (Danio rerio)
        
        IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        IL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)
        
        IL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)
      - IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Danio rerio)
        
        IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        IL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        IL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)
      - JAK1,TYK2 phosphorylate JAK1,TYK2 (Danio rerio)
        
        IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xIL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        IL10RA:JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xIL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)
      - p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)
        
        IL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xIL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of IL10RA [plasma membrane] (Danio rerio)
        
        crfb12 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:Q1RM05

Gene Names

crfb12

Reference Genes

BioGPS Gene:678605 crfb12

CTD Gene:678605 crfb12

ENSEMBL:ENSDARG00000052413

KEGG:dre:678605 crfb12

Monarch:678605 crfb12

NCBI Gene:678605 crfb12

UCSC:Q1RM05 crfb12

Reference Transcript

RefSeq:NM_001040353.1 crfb12

Other Identifiers

13208603

678605

A_15_P107691

A_15_P208206

CJ001313

CJ001314

CJ001315

CUST_9289_PI428451958

DRER10065

DRER29801

ENSDART00000074264

ENSDART00000074264_1

ENSDART00000074264_2

GO:0005515

GT_Xhyb_NM_001040353.1_393535

GT_Xhyb_XM_005165557.1_346175

JP001313

JP001314

JP001315

MADDr01003244

NM_001040353

Participates

as a member of

Homologues of IL10RA [plasma membrane] (Danio rerio)

Other forms of this molecule

crfb12 [extracellular region]

phospho-crfb12 [plasma membrane]

crfb12 [plasma membrane]

phospho-crfb12 [plasma membrane]

crfb12 [plasma membrane]

phospho-crfb12 [plasma membrane]

Inferred From

IL10RA [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001035443.1

ENSEMBL

ENSDART00000074264, ENSDARP00000068753, ENSDARG00000052413

ZFIN

ZDB-GENE-060421-4184