Reactome | tpm4b [cytosol]

tpm4b [cytosol]

Stable Identifier

R-DRE-390548

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

TPM4, A0A1L6UW65

Locations in the PathwayBrowser

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Muscle contraction (Danio rerio)

- Striated Muscle Contraction (Danio rerio)
  - ATP Hydrolysis By Myosin (Danio rerio)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
  - Calcium Binds Troponin-C (Danio rerio)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
    - Inactive Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
  - Myosin Binds ATP (Danio rerio)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
  - Release Of ADP From Myosin (Danio rerio)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Danio rerio)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Danio rerio)
        
        Tropomyosin [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
  - Signaling by Rho GTPases (Danio rerio)
    - RHO GTPase cycle (Danio rerio)
      - RHOV GTPase cycle (Danio rerio)
        
        RHOV binds effectors at the plasma membrane (Danio rerio)
        
        RHOV effectors [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)
        
        RHOV:GTP:RHOV effectors [plasma membrane] (Danio rerio)
        
        RHOV effectors [cytosol] (Danio rerio)
        
        tpm4b [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A1L6UW65

Gene Names

tpm4b

Reference Genes

BioGPS Gene:324244 tpm4b

CTD Gene:324244 tpm4b

ENSEMBL:ENSDARG00000019128

Monarch:324244 tpm4b

NCBI Gene:324244 tpm4b

UCSC:A0A1L6UW65 tpm4b

Reference Transcript

Participates

as a candidate of

RHOV effectors [cytosol] (Danio rerio)

as a member of

Tropomyosin [cytosol] (Danio rerio)

Inferred From

TPM4 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_017213163.1, XP_073768426.1

ZFIN

ZDB-GENE-030131-2964

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