Reactome | cxcr2 [plasma membrane]

cxcr2 [plasma membrane]

Stable Identifier

R-DRE-373805

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

CXCR1, F1Q8T9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (i) signalling events (Danio rerio)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        cxcr2 [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        cxcr2 [plasma membrane] (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Peptide ligand-binding receptors (Danio rerio)
        
        Chemokine receptors bind chemokines (Danio rerio)
        
        Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        cxcr2 [plasma membrane] (Danio rerio)
        
        cxcr2 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:F1Q8T9

Gene Names

cxcr2

Reference Genes

BioGPS Gene:796724 cxcr2

ENSEMBL:ENSDARG00000054975

KEGG:dre:796724 cxcr2

Monarch:796724 cxcr2

NCBI Gene:796724 cxcr2

UCSC:F1Q8T9 cxcr2

Reference Transcript

RefSeq:XM_068223678.1 cxcr2

Other Identifiers

13262847

796724

A_15_P202076

CJ001300

CJ007048

CUST_26688_PI428451953

DRER10800

ENSDART00000077260

ENSDART00000077260_1

ENSDART00000077260_2

GO:0004930

GO:0006935

GO:0007186

GO:0016020

GO:0016494

GT_Spec_XM_001337057.3_185085

JP001300

JP007446

Participates

as a member of

Secretory granule membrane proteins [plasma membrane] (Danio rerio)

as an input of

Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Danio rerio)

as a component of

CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)

Other forms of this molecule

cxcr2 [secretory granule membrane]

cxcr2 [plasma membrane]

Inferred From

CXCR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_068079779.1

ENSEMBL

ENSDARG00000054975, ENSDARP00000071727, ENSDART00000077260

ZFIN

ZDB-GENE-100414-1

Cite Us!