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traf6 [cytosol]
Stable Identifier
R-DRE-2685681
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
K63polyUb-TRAF6, Q6IWL4
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-1 family signaling (Danio rerio)
Interleukin-1 signaling (Danio rerio)
TAK1 is activated within the TAK1 complex (Danio rerio)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TRAF6 is K63 poly-ubiquitinated (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Interleukin-17 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Innate Immune System (Danio rerio)
Toll-like Receptor Cascades (Danio rerio)
Toll Like Receptor 10 (TLR10) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor 2 (TLR2) Cascade (Danio rerio)
Toll Like Receptor TLR1:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor TLR6:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor 3 (TLR3) Cascade (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor 4 (TLR4) Cascade (Danio rerio)
MyD88-independent TLR4 cascade (Danio rerio)
TRIF (TICAM1)-mediated TLR4 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor 5 (TLR5) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Toll Like Receptor 9 (TLR9) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Activated TAK1 phosphorylates MKK4/MKK7 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
activated TAK1 mediates p38 MAPK activation (Danio rerio)
activated human TAK1 phosphorylates MKK3/MKK6 (Danio rerio)
Activated TAK complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
TAK1-dependent IKK and NF-kappa-B activation (Danio rerio)
Ubiquitination of IKBKG by TRAF6 (Danio rerio)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Deubiquitination (Danio rerio)
Ovarian tumor domain proteases (Danio rerio)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Danio rerio)
OTUD7B,TNFAIP3,ZRANB1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Ub-specific processing proteases (Danio rerio)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Danio rerio)
CYLD:K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG [cytosol] (Danio rerio)
K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG [cytosol] (Danio rerio)
traf6 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Death Receptor Signaling (Danio rerio)
p75 NTR receptor-mediated signalling (Danio rerio)
p75NTR signals via NF-kB (Danio rerio)
p75NTR recruits signalling complexes (Danio rerio)
TRAF6 is auto-ubiquitinated (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Danio rerio)
traf6 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6IWL4
Gene Names
traf6
Reference Genes
BioGPS Gene:554561 traf6
ENSEMBL:ENSDARG00000028058
KEGG:dre:554561 traf6
Monarch:554561 traf6
NCBI Gene:554561 traf6
UCSC:Q6IWL4 traf6
Reference Transcript
RefSeq:XM_068222300.1 traf6
RefSeq:NM_001044752.1 traf6
Other Identifiers
13239599
554561
CJ003403
CJ003404
CJ003405
CJ003406
CJ007623
CJ007625
CJ007626
CJ007627
CJ007903
CJ007905
CJ007906
CJ007907
CJ009478
CJ009480
CJ009481
CJ009482
CJ009845
CJ009847
CJ009848
CJ009849
CJ010296
CJ010298
CJ010299
CJ010300
CJ010351
CJ010353
CJ010354
CJ010355
CJ010826
CJ010828
CJ010829
CJ010830
CJ010913
CJ010915
CJ010916
CJ010917
CJ011159
CJ011163
CJ011164
CJ011165
CJ012157
CJ012159
CJ012160
CJ012161
CJ013846
CJ014444
CJ014507
CUST_1753_PI424165564
CUST_1754_PI424165564
CUST_1755_PI424165564
CUST_1756_PI424165564
CUST_1757_PI424165564
CUST_1758_PI424165564
CUST_1759_PI424165564
CUST_1760_PI424165564
DRER04600
Dr.15109.1.A1_at
ENSDART00000038273
ENSDART00000038273_1
ENSDART00000038273_2
GO:0003824
GO:0004842
GO:0005164
GO:0005515
GO:0007165
GO:0008270
GO:0016567
GO:0016740
GO:0042981
GO:0043122
GO:0046872
GO:0140096
GT_Spec_NM_001044752.1_250525
JP003802
JP003803
JP003804
JP003805
JP008021
JP008023
JP008024
JP008025
JP008301
JP008303
JP008304
JP008305
JP009876
JP009878
JP009879
JP009880
JP010243
JP010245
JP010246
JP010247
JP010694
JP010696
JP010697
JP010698
JP010749
JP010751
JP010752
JP010753
JP011224
JP011226
JP011227
JP011228
JP011311
JP011313
JP011314
JP011315
LOL04625
LOL04626
LOL04627
LOL04628
LOL04629
LOL04630
LOL04631
LOL04674
LOL04677
LOL04678
MADDr01007398
NM_001044752
OTTDART00000013635
TC252424
XM_692005
Participates
as a component of
OTUD7B,TNFAIP3,ZRANB1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Danio rerio)
hp-IRAK1:3xK63polyUb-TRAF6 [cytosol] (Danio rerio)
K63pUb-TRAF6:TAB1:TAB2,TAB3:free pUb:p-T-TAK1 [cytosol] (Danio rerio)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Danio rerio)
hp-IRAK1:K63polyUb-TRAF6 [cytosol] (Danio rerio)
p-IRAK2:K63-linked pUb oligo-TRAF6 [cytosol] (Danio rerio)
as a member of
K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG [cytosol] (Danio rerio)
Other forms of this molecule
traf6 [cytosol]
traf6 [cytosol]
traf6 [endosome membrane]
traf6 [endosome membrane]
traf6 [plasma membrane]
traf6 [plasma membrane]
traf6 [cytosol]
Inferred From
K63polyUb-TRAF6 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K63-polyubiquitin [cytosol]) at 124 (in Homo sapiens)
Coordinate
124
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
XP_068078401.1
,
NP_001038217.1
ENSEMBL
ENSDARG00000028058
,
ENSDART00000180847
,
ENSDART00000038273
,
ENSDART00000191675
,
ENSDARP00000151579
,
ENSDARP00000036715
,
ENSDARP00000150477
ZFIN
ZDB-GENE-030131-5735
PRO
Q6IWL4
PDB
5VO0
,
5VNZ
,
6MYD
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