Reactome | wtip [cytosol]

wtip [cytosol]

Stable Identifier

R-DRE-2564698

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

AJUBA, A8DZE6

Locations in the PathwayBrowser

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Cellular responses to stimuli (Danio rerio)

- Cellular responses to stress (Danio rerio)
  - Cellular response to hypoxia (Danio rerio)
    - Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Danio rerio)
      - Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Danio rerio)
        
        hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1:LIMD1,AJUBA,WTIP:PHD2,3 [cytosol] (Danio rerio)
        
        PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Danio rerio)
        
        LIMD1,AJUBA,WTIP [cytosol] (Danio rerio)
        
        Homologues of AJUBA [cytosol] (Danio rerio)
        
        wtip [cytosol] (Danio rerio)
        
        ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Danio rerio)
        
        PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Danio rerio)
        
        LIMD1,AJUBA,WTIP [cytosol] (Danio rerio)
        
        Homologues of AJUBA [cytosol] (Danio rerio)
        
        wtip [cytosol] (Danio rerio)
      - Proteasome proteolyzes ub-HIF-alpha (Danio rerio)
        
        ub-hydroxyPro-HIF-alpha:VCB (with or without LIMD1) [cytosol] (Danio rerio)
        
        ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:CUL2:RBX1:LIMD1,AJUBA,WTIF:PHD2,3 [cytosol] (Danio rerio)
        
        PHD2,3:LIMD1,AJUBA,WTIP:VHL:EloB:EloC:CUL2:RBX1 [cytosol] (Danio rerio)
        
        LIMD1,AJUBA,WTIP [cytosol] (Danio rerio)
        
        Homologues of AJUBA [cytosol] (Danio rerio)
        
        wtip [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:A8DZE6

Gene Names

wtip

Reference Genes

BioGPS Gene:566046 wtip

ENSEMBL:ENSDARG00000103607

KEGG:dre:566046 wtip

Monarch:566046 wtip

NCBI Gene:566046 wtip

UCSC:A8DZE6 wtip

Reference Transcript

RefSeq:NM_001123278.3 wtip

Other Identifiers

13006763

566046

A_15_P167411

A_15_P282611

CUST_8484_PI428451958

DRER14282

ENSDART00000090194_y_1

ENSDART00000093239

GT_Spec_NM_001123278.2_116636

MADDr01011033

OTTDART00000016425

OTTDART00000016425_y_1

OTTDART00000016425_y_2

OTTDART00000016557

XM_689315

Participates

as a member of

Homologues of AJUBA [cytosol] (Danio rerio)

Other forms of this molecule

wtip [cytosol]

Inferred From

AJUBA [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001116750.2

ENSEMBL

ENSDART00000157564, ENSDARG00000103607, ENSDARP00000132856

ZFIN

ZDB-GENE-050419-261

PRO

A8DZE6

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