Reactome | suz12b [nucleoplasm]

suz12b [nucleoplasm]

Stable Identifier

R-DRE-212217

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

SUZ12, B0R1D5

Locations in the PathwayBrowser

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Cell-Cell communication (Danio rerio)

- Cell junction organization (Danio rerio)
  - Cell-cell junction organization (Danio rerio)
    - Adherens junctions interactions (Danio rerio)
      - Regulation of Homotypic Cell-Cell Adhesion (Danio rerio)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Danio rerio)
        
        Regulation of CDH1 Expression and Function (Danio rerio)
        
        Regulation of CDH1 Gene Transcription (Danio rerio)
        
        Negative Regulation of CDH1 Gene Transcription (Danio rerio)
        
        PRC2 (EZH2) core complex methylates nucleosomes at CDH1 gene promoter (Danio rerio)
        
        PRC2 (EZH2) Core [nucleoplasm] (Danio rerio)
        
        suz12b [nucleoplasm] (Danio rerio)
        
        PRC2 (EZH2) Core:H3K27me3-Nucleosome:CDH1 gene [nucleoplasm] (Danio rerio)
        
        PRC2 (EZH2) Core [nucleoplasm] (Danio rerio)
        
        suz12b [nucleoplasm] (Danio rerio)
        
        PRC2 (EZH2) Core:Nucleosome:CDH1 gene [nucleoplasm] (Danio rerio)
        
        PRC2 (EZH2) Core [nucleoplasm] (Danio rerio)
        
        suz12b [nucleoplasm] (Danio rerio)

Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - Regulation of T cell activation by CD28 family (Danio rerio)
    - Co-inhibition by PD-1 (Danio rerio)
      - Regulation of PD-L1(CD274) expression (Danio rerio)
        
        Regulation of PD-L1(CD274) transcription (Danio rerio)
        
        Trimethylation of CD274 gene promoter by EZH2 (Danio rerio)
        
        PRC2 (EZH2) Core [nucleoplasm] (Danio rerio)
        
        suz12b [nucleoplasm] (Danio rerio)
        
        PRC2(EZH2) Core:Nucleosome:CD274 gene promoter [nucleoplasm] (Danio rerio)
        
        PRC2 (EZH2) Core [nucleoplasm] (Danio rerio)
        
        suz12b [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:B0R1D5

Gene Names

suz12b

Reference Genes

BioGPS Gene:561871 suz12b

CTD Gene:561871 suz12b

ENSEMBL:ENSDARG00000098924

KEGG:dre:561871 suz12b

Monarch:561871 suz12b

NCBI Gene:561871 suz12b

UCSC:B0R1D5 suz12b

Reference Transcript

RefSeq:NM_001082824.2 suz12b

Other Identifiers

13219878

13219880

13280426

561871

A_15_P176611

A_15_P186356

A_15_P486145

A_15_P730981

CUST_4297_PI423953333

CUST_4298_PI423953333

CUST_4299_PI423953333

CUST_4300_PI423953333

CUST_4301_PI423953333

CUST_4302_PI423953333

CUST_4303_PI423953333

CUST_4304_PI423953333

CUST_5594_PI428451958

DRER09931

DRER41548

DRER49095

Dr.13720.1.S1_at

Dr.3815.1.A1_at

ENSDART00000073751

ENSDART00000073751_1

ENSDART00000073751_2

GT_Spec_XM_005166189.1_392235

GT_Xhyb_NM_001082824.2_271355

LOLS12798

MADDr01007177

OTTDART00000013500

TC254530

XM_681638

XM_689574

Participates

as a component of

as an input of

Formation of PRC2-EZH2 complex (Danio rerio)

Other forms of this molecule

suz12b [nucleoplasm]

Inferred From

SUZ12 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSDARP00000130332, ENSDARG00000098924, ENSDART00000165271

ZFIN

ZDB-GENE-030131-3255

PRO

B0R1D5

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