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phospho-p-T309,S474-AKT2 [cytosol]
Stable Identifier
R-DRE-202062
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
Q8UUX0
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G1 phase and G1/S transition (Danio rerio)
G1/S Transition (Danio rerio)
Cyclin E associated events during G1/S transition (Danio rerio)
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
S Phase (Danio rerio)
Cyclin A:Cdk2-associated events at S phase entry (Danio rerio)
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
KEAP1-NFE2L2 pathway (Danio rerio)
NFE2L2 translocates from cytosol to nucleoplasm (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
Regulation of TP53 Activity (Danio rerio)
Regulation of TP53 Expression and Degradation (Danio rerio)
Regulation of TP53 Degradation (Danio rerio)
AKT phosphorylates MDM2 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Regulation of T cell activation by CD28 family (Danio rerio)
Co-stimulation by CD28 (Danio rerio)
CD28 dependent PI3K/Akt signaling (Danio rerio)
AKT interacts and phosphorylates Cot (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
AKT phosphorylates targets in the cytosol (Danio rerio)
AKT phosphorylates AKT1S1 (PRAS40) (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
AKT phosphorylates IKKalpha (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
AKT phosphorylates MDM2 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
AKT phosphorylates MKRN1 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
AKT phosphorylates caspase-9 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
PTEN Regulation (Danio rerio)
Regulation of PTEN stability and activity (Danio rerio)
AKT phosphorylates MKRN1 (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
MTOR signalling (Danio rerio)
Activated AKT phosphorylates AKT1S1 (PRAS40) (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by ERBB2 (Danio rerio)
Downregulation of ERBB2 signaling (Danio rerio)
Downregulation of ERBB2:ERBB3 signaling (Danio rerio)
Phosphorylation of USP8 by P-AKT (Danio rerio)
p-T,p-S-AKT [cytosol] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Signaling by Insulin receptor (Danio rerio)
Insulin receptor signalling cascade (Danio rerio)
IRS-mediated signalling (Danio rerio)
PI3K Cascade (Danio rerio)
Activation of AKT2 (Danio rerio)
PDPK1 phosphorylates AKT2 (Danio rerio)
p-T309,S474-AKT2:PIP3 [plasma membrane] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Danio rerio)
IGF1R signaling cascade (Danio rerio)
IRS-related events triggered by IGF1R (Danio rerio)
IRS-mediated signalling (Danio rerio)
PI3K Cascade (Danio rerio)
Activation of AKT2 (Danio rerio)
PDPK1 phosphorylates AKT2 (Danio rerio)
p-T309,S474-AKT2:PIP3 [plasma membrane] (Danio rerio)
phospho-p-T309,S474-AKT2 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q8UUX0
Reference Genes
BioGPS Gene:378972
ENSEMBL:ENSDARG00000011219
KEGG:dre:378972
Monarch:378972
NCBI Gene:378972
UCSC:Q8UUX0
Reference Transcript
RefSeq:NM_198146.2
Other Identifiers
13064996
378972
A_15_P101103
A_15_P206271
A_15_P366370
A_15_P720706
CJ003217
CJ003222
CJ003223
CJ013674
CJ013777
CJ014351
CJ014494
CUST_11595_PI428451953
CUST_12824_PI428451958
DRER03444
DrAffx.1.41.S1_at
ENSDART00000026767
ENSDART00000026767_1
ENSDART00000026767_2
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0006468
GO:0016740
GO:0140096
GT_Xhyb_NM_198146.2_195745
GT_Xhyb_XM_005173637.1_273665
JP003587
JP003592
JP003593
LOLS02534
MADDr01008218
NM_198146
OTTDART00000016062
Participates
as a member of
p-T,p-S-AKT [cytosol] (Danio rerio)
as a component of
p-T309,S474-AKT2:PIP3 [plasma membrane] (Danio rerio)
as a candidate of
p-T,p-S-AKT [cytosol] (Danio rerio)
Other forms of this molecule
phospho-p-T309-AKT2 [cytosol]
AKT2 [cytosol]
AKT2 [plasma membrane]
phospho-p-S474-AKT2 [plasma membrane]
phospho-p-T309,S474-AKT2 [nucleoplasm]
Inferred From
p-T309,S474-AKT2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 309 (in Homo sapiens)
Coordinate
309
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 474 (in Homo sapiens)
Coordinate
474
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_937789.1
ENSEMBL
ENSDARP00000023119
,
ENSDARG00000011219
,
ENSDART00000026767
ZFIN
ZDB-GENE-031007-5
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