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PP2A [cytosol]
Stable Identifier
R-DRE-196206
Type
Complex
Species
Danio rerio
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
Mitotic Spindle Checkpoint (Danio rerio)
Amplification of signal from the kinetochores (Danio rerio)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Danio rerio)
MAD2 associates with the Mad1 kinetochore complex (Danio rerio)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Danio rerio)
Mad1:kinetochore complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Mad1:kinetochore complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
MAD2 converted to an inhibitory state via interaction with Mad1 (Danio rerio)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Danio rerio)
Mad1:kinetochore complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Mad1 binds kinetochore (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Mad1:kinetochore complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Release of activated MAD2 from kinetochores (Danio rerio)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Danio rerio)
Mad1:kinetochore complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Mad1:kinetochore complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Metaphase and Anaphase (Danio rerio)
Mitotic Anaphase (Danio rerio)
Separation of Sister Chromatids (Danio rerio)
ESPL1 (Separase) cleaves centromeric cohesin (Danio rerio)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Separation of sister chromatids (Danio rerio)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Mitotic Prometaphase (Danio rerio)
Resolution of Sister Chromatid Cohesion (Danio rerio)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Danio rerio)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Kinetochore assembly (Danio rerio)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
PP2A-B56 dephosphorylates centromeric cohesin (Danio rerio)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Phosphorylation of cohesin by PLK1 at centromeres (Danio rerio)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
Microtubule-bound kinetochore [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate Formins (Danio rerio)
AURKB phosphorylates DIAPH2-2 at kinetochores (Danio rerio)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Signaling by WNT (Danio rerio)
Degradation of beta-catenin by the destruction complex (Danio rerio)
AXIN is phosphorylated in the destruction complex (Danio rerio)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Danio rerio)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Association of beta-catenin with the destruction complex (Danio rerio)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Beta-catenin phosphorylation cascade (Danio rerio)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Danio rerio)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Danio rerio)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Danio rerio)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Danio rerio)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Degradation of ubiquitinated beta catenin by the proteasome (Danio rerio)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Danio rerio)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Danio rerio)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Danio rerio)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
Phosphorylation of APC component of the destruction complex (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
PP2A [cytosol] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
PP2A regulatory subunit B56 [cytosol]
(Danio rerio)
PP2A-catalytic subunit C [cytosol]
(Danio rerio)
PP2A-subunit A [cytosol]
(Danio rerio)
Participates
as a component of
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Danio rerio)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Danio rerio)
Kinetochore [cytosol] (Danio rerio)
Inferred From
PP2A [cytosol]
(Homo sapiens)
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