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cdkn1ba [nucleoplasm]
Stable Identifier
R-DRE-182563
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
nucleoplasm
Synonyms
CDKN1B, Q5RGY9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
G1/S DNA Damage Checkpoints (Danio rerio)
p53-Dependent G1/S DNA damage checkpoint (Danio rerio)
p53-Dependent G1 DNA Damage Response (Danio rerio)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
Mitotic G1 phase and G1/S transition (Danio rerio)
G1 Phase (Danio rerio)
Cyclin D associated events in G1 (Danio rerio)
Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Danio rerio)
p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Danio rerio)
CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Danio rerio)
Cyclin D:CDK4,CDK6:CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
G1/S Transition (Danio rerio)
Cyclin E associated events during G1/S transition (Danio rerio)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
SCF(Skp2)-mediated degradation of p27/p21 (Danio rerio)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Danio rerio)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Translocation of p27 to the nucleoplasm (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
S Phase (Danio rerio)
Cyclin A:Cdk2-associated events at S phase entry (Danio rerio)
Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
SCF(Skp2)-mediated degradation of p27/p21 (Danio rerio)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Danio rerio)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Translocation of p27 to the nucleoplasm (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular Senescence (Danio rerio)
DNA Damage/Telomere Stress Induced Senescence (Danio rerio)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Senescence-Associated Secretory Phenotype (SASP) (Danio rerio)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Transcription of Cell Cycle Genes (Danio rerio)
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (Danio rerio)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Danio rerio)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Extra-nuclear estrogen signaling (Danio rerio)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Danio rerio)
CDKN1B is phosphorylated in response to estrogen (Danio rerio)
cdkn1ba [nucleoplasm] (Danio rerio)
External Reference Information
External Reference
UniProt:Q5RGY9
Gene Names
cdkn1ba
Reference Genes
BioGPS Gene:402862 cdkn1ba
CTD Gene:402862 cdkn1ba
ENSEMBL:ENSDARG00000029018
KEGG:dre:402862 cdkn1ba
Monarch:402862 cdkn1ba
NCBI Gene:402862 cdkn1ba
UCSC:Q5RGY9 cdkn1ba
Reference Transcript
RefSeq:NM_001013268.1 cdkn1ba
Other Identifiers
13188493
402862
A_15_P105830
CJ009890
CJ009891
CJ009892
CJ011356
CJ011357
CJ011358
CUST_7601_PI428451958
DRER05975
DRER45453
ENSDART00000049061
ENSDART00000049061_1
ENSDART00000049061_2
GO:0000082
GO:0004860
GO:0004861
GO:0005634
GO:0005737
GO:0005768
GO:0045930
GO:0050680
GO:0051087
GO:0051726
GO:0098772
GT_Xhyb_NM_001013268.1_196995
GT_Xhyb_XM_005164730.1_101721
JP010288
JP010289
JP010290
MADDr01005369
OTTDART00000009269
XM_686521
Participates
as an input of
CDKN1B is phosphorylated in response to estrogen (Danio rerio)
Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Danio rerio)
Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Danio rerio)
as a component of
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm] (Danio rerio)
Cyclin E:CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Danio rerio)
as an output of
Translocation of p27 to the nucleoplasm (Danio rerio)
as a member of
CDKN1A,CDKN1B,(CDKN1C) [nucleoplasm] (Danio rerio)
Other forms of this molecule
phospho-cdkn1ba [cytosol]
phospho-cdkn1ba [nucleoplasm]
phospho-cdkn1ba [cytosol]
phospho-cdkn1ba [nucleoplasm]
cdkn1ba [cytosol]
phospho-cdkn1ba [cytosol]
phospho-cdkn1ba [nucleoplasm]
Inferred From
CDKN1A,CDKN1B [nucleoplasm]
(Homo sapiens)
CDKN1B [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001013286.1
ENSEMBL
ENSDARP00000049060
,
ENSDARG00000029018
,
ENSDART00000049061
ZFIN
ZDB-GENE-040812-3
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