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cul5a [cytosol]
Stable Identifier
R-DRE-180528
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
CUL5, F1REN0
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
Interaction of E3 with substrate and E2-Ub complex (Danio rerio)
Ag-substrate:E3:E2:Ub [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
Polyubiquitination of substrate (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
E3:K48-polyubiquitinated substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
E3:Ub:substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
Release of E3 from polyubiquitinated substrate (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
E3:K48-polyubiquitinated substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
Transfer of Ub from E2 to substrate and release of E2 (Danio rerio)
Ag-substrate:E3:E2:Ub [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
E3:Ub:substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
RBX1-CUL5-EloB/C-SOCS [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RBX1:CUL5:EloB/C:LRRC41 [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Neddylation (Danio rerio)
AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Danio rerio)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Danio rerio)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Danio rerio)
CRL E3 ubiquitin ligases [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
CRL E3 ubiquitin ligases [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Danio rerio)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Danio rerio)
CRL E3 ubiquitin ligases [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Danio rerio)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Danio rerio)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
cul5a [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by ERBB2 (Danio rerio)
Downregulation of ERBB2 signaling (Danio rerio)
CUL5 mediates ubiquitination of ERBB2 (Danio rerio)
cul5a [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:F1REN0
Gene Names
cul5a
Reference Genes
BioGPS Gene:327215 cul5a
CTD Gene:327215 cul5a
ENSEMBL:ENSDARG00000069742
KEGG:dre:327215 cul5a
Monarch:327215 cul5a
NCBI Gene:327215 cul5a
UCSC:F1REN0 cul5a
Other Identifiers
13024572
327215
A_15_P105842
A_15_P639661
A_15_P658076
CJ012095
CJ012097
CUST_2937_PI428451953
DRER18376
Dr.10370.1.S1_at
ENSDART00000110111
GO:0006511
GO:0031461
GO:0031625
GT_Xhyb_XM_005161006.1_101031
LOLS08331
TC250830
ZV700S00000123
Participates
as a component of
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Danio rerio)
CRL5 E3 ubiquitin ligase [cytosol] (Danio rerio)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Danio rerio)
Cul5-SCF complex [cytosol] (Danio rerio)
Other forms of this molecule
cul5a [cytosol]
Inferred From
CUL5 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001314988.1
ENSEMBL
ENSDARG00000112542
,
ENSDARG00000116292
,
ENSDART00000188296
,
ENSDARP00000100474
,
ENSDARP00000157577
,
ENSDARG00000069742
,
ENSDART00000190789
,
ENSDARP00000150867
,
ENSDART00000110111
ZFIN
ZDB-GENE-030131-5426
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