Reactome | phospho-nfkbib [cytosol]

phospho-nfkbib [cytosol]

Stable Identifier

R-DRE-177670

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

p-S19,S23-NFKBIB, B3DJC4

Locations in the PathwayBrowser

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Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - Signaling by the B Cell Receptor (BCR) (Danio rerio)
    - Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
      - Activation of NF-kappaB in B cells (Danio rerio)
        
        Activated IKK phosphorylates I-kappaB (Danio rerio)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Danio rerio)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Danio rerio)
        
        p-IKB alpha,beta,epsilon [cytosol] (Danio rerio)
        
        phospho-nfkbib [cytosol] (Danio rerio)
        
        SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Danio rerio)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Danio rerio)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Danio rerio)
        
        p-IKB alpha,beta,epsilon [cytosol] (Danio rerio)
        
        phospho-nfkbib [cytosol] (Danio rerio)
        
        NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Danio rerio)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Danio rerio)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Danio rerio)
        
        p-IKB alpha,beta,epsilon [cytosol] (Danio rerio)
        
        phospho-nfkbib [cytosol] (Danio rerio)
        
        SCF-beta-TrCP ubiquitinylates IkB (Danio rerio)
        
        NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Danio rerio)
        
        NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Danio rerio)
        
        NF-kappaB p50:c-Rel:p-IKB [cytosol] (Danio rerio)
        
        p-IKB alpha,beta,epsilon [cytosol] (Danio rerio)
        
        phospho-nfkbib [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:B3DJC4

Gene Names

nfkbib

Reference Genes

BioGPS Gene:797834 nfkbib

ENSEMBL:ENSDARG00000030087

KEGG:dre:797834 nfkbib

Monarch:797834 nfkbib

NCBI Gene:797834 nfkbib

UCSC:B3DJC4 nfkbib

Reference Transcript

RefSeq:NM_001128795.1 nfkbib

Other Identifiers

13196562

797834

A_15_P109856

A_15_P146856

CUST_5258_PI428451958

DRER05456

Dr.5973.1.A1_at

ENSDART00000045036

ENSDART00000045036_1

ENSDART00000045036_2

GO:0005515

GT_Spec_NM_001128795.1_177465

LOLT00213

MADDr01013339

OTTDART00000022299

XM_691811

XM_696085

Participates

as a member of

p-IKB alpha,beta,epsilon [cytosol] (Danio rerio)

Other forms of this molecule

phospho-nfkbib [cytosol]

nfkbib [cytosol]

Inferred From

p-S19,S23-NFKBIB [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 19 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 23 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_001122267.1

ENSEMBL

ENSDARG00000030087, ENSDARP00000045035, ENSDART00000045036

ZFIN

ZDB-GENE-070705-529

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