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cdc16 [cytosol]
Stable Identifier
R-DRE-174156
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
CDC16, Q32PS0
Locations in the PathwayBrowser
Expand all
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
Mitotic Spindle Checkpoint (Danio rerio)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Danio rerio)
Inactivation of APC/C via direct inhibition of the APC/C complex (Danio rerio)
Binding of the MCC complex to the APC/C complex (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Metaphase and Anaphase (Danio rerio)
Mitotic Anaphase (Danio rerio)
Separation of Sister Chromatids (Danio rerio)
Association of Securin with Cdc20:APC/C complex (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
CDC20:p-APC/C:PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Degradation of multiubiquitinated Securin (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Danio rerio)
CDC20:p-APC/C:PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Regulation of mitotic cell cycle (Danio rerio)
APC/C-mediated degradation of cell cycle proteins (Danio rerio)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Danio rerio)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Danio rerio)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Degradation of multiubiquitinated cell cycle proteins (Danio rerio)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Danio rerio)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Danio rerio)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Danio rerio)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Danio rerio)
APC/C:Cdc20 mediated degradation of mitotic proteins (Danio rerio)
APC/C:Cdc20 mediated degradation of Cyclin B (Danio rerio)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Degradation of multiubiquitinated Cyclin B (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Danio rerio)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Danio rerio)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Danio rerio)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
APC/C:Cdc20 mediated degradation of Securin (Danio rerio)
Association of Securin with Cdc20:APC/C complex (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
CDC20:p-APC/C:PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Degradation of multiubiquitinated Securin (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Danio rerio)
CDC20:p-APC/C:PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Danio rerio)
APC-Cdc20 mediated degradation of Nek2A (Danio rerio)
Association of Nek2A with MCC:APC/C (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Nek2A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Degradation of multiubiquitinated Nek2A (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Multiubiquitinated Nek2A [cytosol] (Danio rerio)
Nek2A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Multiubiquitination of Nek2A (Danio rerio)
Multiubiquitinated Nek2A [cytosol] (Danio rerio)
Nek2A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Nek2A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Danio rerio)
Association of Cyclin A with the APC/C (Danio rerio)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Degradation multiubiquitinated Cyclin A (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Danio rerio)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Danio rerio)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Danio rerio)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Danio rerio)
Association of Cdh1 with the APC/C (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Dissociation of Cdc20 from APC/C complex (Danio rerio)
CDC20:p-APC/C [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Regulation of APC/C activators between G1/S and early anaphase (Danio rerio)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Danio rerio)
Inactivation of APC/C via direct inhibition of the APC/C complex (Danio rerio)
Binding of the MCC complex to the APC/C complex (Danio rerio)
MCC:APC/C complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
S Phase (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
DNA Replication (Danio rerio)
Synthesis of DNA (Danio rerio)
Switching of origins to a post-replicative state (Danio rerio)
CDK-mediated phosphorylation and removal of Cdc6 (Danio rerio)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Danio rerio)
phospho-APC/C:Cdh1 complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
Interaction of E3 with substrate and E2-Ub complex (Danio rerio)
Ag-substrate:E3:E2:Ub [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Polyubiquitination of substrate (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
E3:K48-polyubiquitinated substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
E3:Ub:substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Release of E3 from polyubiquitinated substrate (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
E3:K48-polyubiquitinated substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
Transfer of Ub from E2 to substrate and release of E2 (Danio rerio)
Ag-substrate:E3:E2:Ub [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
E3:Ub:substrate [cytosol] (Danio rerio)
E3 ligases in proteasomal degradation [cytosol] (Danio rerio)
APC/C E3 ligase complex [cytosol] (Danio rerio)
cdc16 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q32PS0
Gene Names
cdc16
Reference Genes
BioGPS Gene:562014 cdc16
ENSEMBL:ENSDARG00000055470
KEGG:dre:562014 cdc16
Monarch:562014 cdc16
NCBI Gene:562014 cdc16
UCSC:Q32PS0 cdc16
Reference Transcript
RefSeq:NM_001037389.2 cdc16
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Danio rerio)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Danio rerio)
Other forms of this molecule
cdc16 [nucleoplasm]
Inferred From
CDC16 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001032466.2
ZFIN
ZDB-GENE-051113-132
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