Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GNA11 [plasma membrane]
Stable Identifier
R-DRE-167446
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
plasma membrane
Synonyms
Q6AZW4
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Danio rerio)
Cellular responses to mechanical stimuli (Danio rerio)
Response of endothelial cells to shear stress (Danio rerio)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Danio rerio)
Phosphorylation of PDPK1 on serine-241 (Danio rerio)
G-protein alpha (q/11) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
mTORC2 phosphorylates AKT1 on serine-473 (Danio rerio)
G-protein alpha (q/11) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Hemostasis (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
Signal amplification (Danio rerio)
ADP signalling through P2Y purinoceptor 1 (Danio rerio)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Thromboxane signalling through TP receptor (Danio rerio)
Gq activation by TP receptor (Danio rerio)
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Danio rerio)
G protein-GTP [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
TP receptor:Thromboxane A2:G-protein Gq (inactive) [plasma membrane] (Danio rerio)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Danio rerio)
G-protein alpha (q/11):GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Thrombin signalling through proteinase activated receptors (PARs) (Danio rerio)
Thrombin-activated PARs activate Gq (Danio rerio)
Thrombin-activated PAR:Gq (active) [plasma membrane] (Danio rerio)
G protein-GTP [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Thrombin-activated PARs:Gq (inactive) [plasma membrane] (Danio rerio)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Danio rerio)
G-protein alpha (q/11):GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Opioid Signalling (Danio rerio)
G-protein activation (Danio rerio)
G-protein alpha subunit is inactivated (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha:GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
The receptor:G-protein complex binds GTP (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Opioid:MOR:G protein-GTP complex [plasma membrane] (Danio rerio)
G protein-GTP [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Opioid:MOR:G-protein complex [plasma membrane] (Danio rerio)
Heterotrimeric G-protein [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
The receptor:G-protein complex releases GDP (Danio rerio)
Opioid:MOR:G protein-GDP complex [plasma membrane] (Danio rerio)
G protein-GDP complex [plasma membrane] (Danio rerio)
G-protein alpha:GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Opioid:MOR:G-protein complex [plasma membrane] (Danio rerio)
Heterotrimeric G-protein [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein mediated events (Danio rerio)
PLC beta mediated events (Danio rerio)
Inactivation of PLC beta (Danio rerio)
Activated PLC beta 1/4 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha:GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
PIP2 hydrolysis (Danio rerio)
Activated PLC beta 1/4 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q) signalling events (Danio rerio)
Active G alpha (q) binds RGS proteins (Danio rerio)
G alpha (q):GTP:RGS [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Active Gq binds BTK (Danio rerio)
Active Gq:BTK [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
BTK in active Gq-BTK complex is activated (Danio rerio)
Active Gq:BTK [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha (q/11):GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q) binds to Trio family RhoGEFs (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q) in G (q):RGS complex is inactivated (Danio rerio)
G alpha (q):GDP:RGS [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q):GTP:RGS [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q) inhibits PI3K alpha (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha (q/11):PI3K alpha [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G alpha (q):RGS dissociates to inactive G alpha (q) (Danio rerio)
G alpha (q):GDP:RGS [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha (q/11):GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
GRK2 sequesters activated Gq (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G-protein alpha (q):GRK2 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Gq-BTK complex dissociates to Active BTK and Gq (Danio rerio)
Active Gq:BTK [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Danio rerio)
G protein-GTP [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Danio rerio)
Heterotrimeric G-protein Gq/11 (inactive) [plasma membrane] (Danio rerio)
G-protein alpha (q/11):GDP [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
PLC-beta hydrolyses PIP2 to DAG and IP3 (Danio rerio)
Activated PLC beta 1/4 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
PLC-beta:G-alpha(q/11):DAG:IP3 [plasma membrane] (Danio rerio)
Activated PLC beta 1/4 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
PLC-beta:G-alpha(q/11):PIP2 [plasma membrane] (Danio rerio)
Activated PLC beta 1/4 [plasma membrane] (Danio rerio)
G protein alpha:GTP complex [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
GNA11 [plasma membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:Q6AZW4
Reference Genes
BioGPS Gene:445297
ENSEMBL:ENSDARG00000035178
KEGG:dre:445297
Monarch:445297
NCBI Gene:445297
UCSC:Q6AZW4
Reference Transcript
RefSeq:NM_001003753.1
Participates
as a member of
G-protein alpha (q/11) [plasma membrane] (Danio rerio)
G-protein alpha (q/11/14/15) [plasma membrane] (Danio rerio)
as a candidate of
G(q) alpha 11,14,15,Q [plasma membrane] (Danio rerio)
Inferred From
GNA11 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001003753.1
ZFIN
ZDB-GENE-040808-7
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
