Reactome | xpo1b [cytosol]

xpo1b [cytosol]

Stable Identifier

R-DRE-165539

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

XPO1, A0A8M9PPG9

Locations in the PathwayBrowser

Expand all

Cell Cycle (Danio rerio)

- Cell Cycle Checkpoints (Danio rerio)
  - Mitotic Spindle Checkpoint (Danio rerio)
    - Amplification of signal from the kinetochores (Danio rerio)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Danio rerio)
        
        MAD2 associates with the Mad1 kinetochore complex (Danio rerio)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Danio rerio)
        
        Mad1:kinetochore complex [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Mad1:kinetochore complex [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Danio rerio)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Danio rerio)
        
        Mad1:kinetochore complex [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Mad1 binds kinetochore (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Mad1:kinetochore complex [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Release of activated MAD2 from kinetochores (Danio rerio)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Danio rerio)
        
        Mad1:kinetochore complex [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Mad1:kinetochore complex [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
- Cell Cycle, Mitotic (Danio rerio)
  - M Phase (Danio rerio)
    - Mitotic Metaphase and Anaphase (Danio rerio)
      - Mitotic Anaphase (Danio rerio)
        
        Separation of Sister Chromatids (Danio rerio)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Danio rerio)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Separation of sister chromatids (Danio rerio)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Sister Centromere:Kinetochore:Microtubules [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
    - Mitotic Prometaphase (Danio rerio)
      - Resolution of Sister Chromatid Cohesion (Danio rerio)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Danio rerio)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Kinetochore assembly (Danio rerio)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Danio rerio)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Danio rerio)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Danio rerio)
        
        Microtubule-bound kinetochore [cytosol] (Danio rerio)
        
        Kinetochore [cytosol] (Danio rerio)
        
        xpo1b [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A8M9PPG9

Gene Names

xpo1b

Reference Genes

BioGPS Gene:561138 xpo1b

CTD Gene:561138 xpo1b

ENSEMBL:ENSDARG00000063229

KEGG:dre:561138 xpo1b

Monarch:561138 xpo1b

NCBI Gene:561138 xpo1b

UCSC:A0A8M9PPG9 xpo1b

Reference Transcript

RefSeq:XM_009293053.4 xpo1b

Other Identifiers

13045490

561138

A_15_P101133

A_15_P119073

A_15_P438735

A_15_P458425

A_15_P670116

CJ008182

CJ008183

CJ008885

CJ008886

CUST_2106_PI428451953

DRER14083

DRER51476

DRER52758

DRER53875

ENSDART00000092188

GO:0005049

GO:0006611

GO:0006886

GO:0006913

GO:0031267

GO:0140104

GT_Spec_XM_001919762.3_143576

JP008580

JP008581

JP009283

JP009284

LOLS14340

XM_684542

Participates

as an output of

XPO1-dependent export of p-S69,S73 MITF-M (Danio rerio)

as a component of

Other forms of this molecule

xpo1b [nucleoplasm]

Inferred From

XPO1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_009291328.1

ENSEMBL

ENSDART00000154823, ENSDARG00000063229, ENSDARP00000128611

ZFIN

ZDB-GENE-070530-6

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