Reactome | rdx [cytosol]

rdx [cytosol]

Stable Identifier

R-DME-9929374

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

Q9VFP2

Locations in the PathwayBrowser

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Immune System (Drosophila melanogaster)

- Adaptive Immune System (Drosophila melanogaster)
  - Regulation of T cell activation by CD28 family (Drosophila melanogaster)
    - Co-inhibition by PD-1 (Drosophila melanogaster)
      - Regulation of PD-L1(CD274) expression (Drosophila melanogaster)
        
        Regulation of PD-L1(CD274) Post-translational modification (Drosophila melanogaster)
        
        SPOP-mediated proteasomal degradation of PD-L1(CD274) (Drosophila melanogaster)
        
        CDK4:CCND1 phosphorylates SPOP (Drosophila melanogaster)
        
        Homologues of p-S6-SPOP [cytosol] (Drosophila melanogaster)
        
        rdx [cytosol] (Drosophila melanogaster)
        
        p-S6-SPOP binds YWHAG (Drosophila melanogaster)
        
        Homologues of p-S6-SPOP [cytosol] (Drosophila melanogaster)
        
        rdx [cytosol] (Drosophila melanogaster)
        
        p-S6-SPOP:YWHAG [cytosol] (Drosophila melanogaster)
        
        Homologues of p-S6-SPOP [cytosol] (Drosophila melanogaster)
        
        rdx [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VFP2 rdx

Gene Names

rdx, HIB, CG12537

Chain

chain:1-829

Reference Genes

BioGPS Gene:41704 RDX

KEGG:dme:Dmel_CG12537 RDX

Monarch:41704 RDX

NCBI Gene:41704 RDX

UCSC:Q9VFP2 RDX

Reference Transcript

Participates

as a member of

Homologues of p-S6-SPOP [cytosol] (Drosophila melanogaster)

Other forms of this molecule

RDX [nucleoplasm]

rdx [nucleoplasm]

rdx [cytosol]

Inferred From

p-S6-SPOP [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_731876.2, NP_731875.2, NP_731877.1, NP_650326.3, NP_650325.1

ENSEMBL

FBtr0100361, FBgn0264493, FBpp0099767

FlyBase

FBgn0264493

PRO

Q9VFP2

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7KNM2	6	lwr [nucleoplasm] (R-DME-912481) lwr [nucleoplasm] (R-DME-3730619) lwr [cytosol] (R-DME-4655342) lwr [cytosol] (R-DME-4656944) lwr [nucleoplasm] (R-DME-3730629) lwr [nuclear envelope] (R-DME-4655408)	0.488	2

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