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Med [nucleoplasm]
Stable Identifier
R-DME-9773863
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Ub-SMAD4, O62609
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Drosophila melanogaster)
Med [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Drosophila melanogaster)
Med [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O62609
Gene Names
Med
Reference Genes
BioGPS Gene:43725 Med
ENSEMBL:FBgn0288966
FlyBase:FBgn0288966
KEGG:dme:Dmel_CG1775 Med
Monarch:43725 Med
NCBI Gene:43725 Med
UCSC:O62609 Med
Reference Transcript
RefSeq:NM_079871.4 Med
RefSeq:NM_170560.2 Med
Other Identifiers
154087_at
1637202_a_at
43725
GO:0000122
GO:0000977
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0001745
GO:0003677
GO:0005515
GO:0005634
GO:0005667
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0007476
GO:0007480
GO:0007507
GO:0009653
GO:0009950
GO:0009953
GO:0030154
GO:0030509
GO:0030707
GO:0030718
GO:0031290
GO:0032924
GO:0035019
GO:0040024
GO:0042078
GO:0045705
GO:0045887
GO:0045944
GO:0046872
GO:0048666
GO:0048856
GO:0050793
GO:0051239
GO:0060255
GO:0060395
GO:0070411
GO:0071144
GO:0080090
GO:0090571
Participates
as an input of
Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Drosophila melanogaster)
Other forms of this molecule
phospho-Med [nucleoplasm]
Med [cytosol]
Med [cytosol]
Med [nucleoplasm]
Inferred From
Ub-SMAD4 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (Ub [nucleoplasm]) at unknown position
Modification
Ub [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_733439.2
,
NP_524610.1
FlyBase
FBgn0288966
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