Reactome | VAChT [clathrin-coated endocytic vesicle membrane]

VAChT [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-DME-8869109

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

SLC18A3, O17444

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - Clathrin-mediated endocytosis (Drosophila melanogaster)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        VAChT [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
    - RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        VAChT [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:O17444

Gene Names

VAChT

Reference Genes

BioGPS Gene:42795 VAChT

ENSEMBL:FBgn0270928

FlyBase:FBgn0270928

KEGG:dme:Dmel_CG32848 VAChT

Monarch:42795 VAChT

NCBI Gene:42795 VAChT

UCSC:O17444 VAChT

Reference Transcript

RefSeq:NM_057790.5 VAChT

Other Identifiers

1636264_at

42795

GO:0005277

GO:0006836

GO:0007268

GO:0015695

GO:0016020

GO:0022857

GO:0030121

GO:0030122

GO:0042908

GO:0042910

GO:0043195

GO:0055085

GO:1901374

Participates

as a member of

AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Other forms of this molecule

VAChT [plasma membrane]

VAChT [clathrin-sculpted acetylcholine transport vesicle membrane]

Inferred From

SLC18A3 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_477138.1

ENSEMBL

FBtr0083671, FBpp0083086, FBgn0270928

FlyBase

FBgn0270928

PRO

O17444

GlyGen

O17444

Cite Us!