Reactome | Dmel\CG11898 [clathrin-coated endocytic vesicle membrane]

Dmel\CG11898 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-DME-8869104-6

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

PolyUb-CFTR, Q9VAN4

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - Clathrin-mediated endocytosis (Drosophila melanogaster)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        Homologues of PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        Dmel\CG11898 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
    - RAB5 and GAPVD1 bind AP-2 (Drosophila melanogaster)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        AP-2 YXXPhi cargo [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        Homologues of PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)
        
        Dmel\CG11898 [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VAN4

Gene Names

Dmel\CG11898

Reference Genes

BioGPS Gene:43451 Dmel\CG11898

ENSEMBL:FBgn0039645

FlyBase:FBgn0039645

KEGG:dme:Dmel_CG11898 Dmel\CG11898

Monarch:43451 Dmel\CG11898

NCBI Gene:43451 Dmel\CG11898

UCSC:Q9VAN4 Dmel\CG11898

Reference Transcript

RefSeq:NM_143422.3 Dmel\CG11898

Other Identifiers

150810_at

1628954_at

43451

GO:0000166

GO:0005524

GO:0005886

GO:0016020

GO:0016787

GO:0016887

GO:0042626

GO:0055085

GO:0140359

Participates

as a member of

Homologues of PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

Other forms of this molecule

Dmel\CG11898 [plasma membrane]

Dmel\CG11898 [platelet dense granule membrane]

Dmel\CG11898 [plasma membrane]

Dmel\CG11898 [endoplasmic reticulum membrane]

Inferred From

PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [cytosol]) at unknown position

Modification

PolyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_651679.2

FlyBase

FBgn0039645