Reactome | ORMDL [endoplasmic reticulum membrane]

ORMDL [endoplasmic reticulum membrane]

Stable Identifier

R-DME-8865584

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endoplasmic reticulum membrane

Synonyms

ORMDL1, Q9VP04

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9VP04

Gene Names

ORMDL

Reference Genes

BioGPS Gene:40404 ORMDL

ENSEMBL:FBgn0037110

Flybase:FBgn0037110

KEGG Gene (Drosophila melanogaster):Dmel_CG14577 ORMDL

Monarch:40404 ORMDL

NCBI Gene:40404 ORMDL

UCSC:Q9VP04 ORMDL

Reference Transcript

RefSeq:NM_168929.2 ORMDL

Other Identifiers

149195_at

1630754_at

40404

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005829

GO:0006629

GO:0006672

GO:0008150

GO:0009058

GO:0016020

GO:0016021

GO:0032991

GO:0034641

GO:0035339

GO:0042592

GO:0043226

GO:0090156

GO:1900060

This entity regulates

Negatively

palmitoyl-CoA + serine => 3-ketosphinganine + CoASH + CO2 (Drosophila melanogaster)

Other forms of this molecule

ORMDL [specific granule membrane]

ORMDL [plasma membrane]

ORMDL [secretory granule membrane]

Inferred From

ORMDL1,2,3 [endoplasmic reticulum membrane] (Homo sapiens)

ORMDL2 [endoplasmic reticulum membrane] (Homo sapiens)

ORMDL1 [endoplasmic reticulum membrane] (Homo sapiens)

ORMDL3 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_730669.1

Flybase

FBgn0037110

PRO

Q9VP04

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q2PDR0	1	Dpm3 [endoplasmic reticulum membrane] (R-DME-162825)	0.488	2
UniProt:O97172 U729			0.488	2
UniProt:D2NUI8 D2NUI8			0.488	2
UniProt:A2VEE1 A2VEE1			0.488	2
UniProt:A2VER2 A2VER2			0.488	2
UniProt:Q6NP72 Q6NP72			0.488	2
UniProt:B3DND5 B3DND5			0.488	2
UniProt:P23380	7	Vha16-1 [endosome membrane] (R-DME-912591) Vha16-1 [plasma membrane] (R-DME-6806254) Vha16-1 [lysosomal membrane] (R-DME-9640194) Vha16-1 [phagocytic vesicle membrane] (R-DME-1222603) Vha16-1 [ficolin-1-rich granule membrane] (R-DME-6800908) Vha16-1 [azurophil granule membrane] (R-DME-6799363) Vha16-1 [tertiary granule membrane] (R-DME-6800991)	0.488	2
UniProt:Q058V3 Q058V3			0.488	2
UniProt:Q9W1M3 Q9W1M3			0.488	2
UniProt:B5X533 B5X533			0.488	2
UniProt:B9EQV3 B9EQV3			0.488	2
UniProt:Q9VHS6 Q9VHS6			0.488	2
UniProt:Q9V9Z1	1	mRpL32 [mitochondrial inner membrane] (R-DME-5368195)	0.488	2
UniProt:Q8SX37	1	Pis [endoplasmic reticulum membrane] (R-DME-1498749)	0.488	2
UniProt:Q8IQL2 Q8IQL2			0.488	2
UniProt:Q9VPQ7	1	Spp [endoplasmic reticulum membrane] (R-DME-9708544)	0.488	2

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