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Roc2 [cytosol]
Stable Identifier
R-DME-8863132
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
RNF7 (RBX2), Q7JWH5
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Neddylation (Drosophila melanogaster)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Drosophila melanogaster)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Drosophila melanogaster)
CRL E3 ubiquitin ligases [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
CRL E3 ubiquitin ligases [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Drosophila melanogaster)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Drosophila melanogaster)
NEDD8-CRL5 E3 ligase [cytosol] (Drosophila melanogaster)
Roc2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JWH5
Gene Names
Roc2
Reference Genes
BioGPS Gene:36246 Roc2
ENSEMBL:FBgn0044020
Flybase:FBgn0044020
KEGG Gene (Drosophila melanogaster):Dmel_CG8998 Roc2
Monarch:36246 Roc2
NCBI Gene:36246 Roc2
UCSC:Q7JWH5 Roc2
Reference Transcript
RefSeq:NM_136847.3 Roc2
RefSeq:NM_001169648.2 Roc2
Other Identifiers
1625617_at
36246
GO:0003824
GO:0005634
GO:0005737
GO:0005829
GO:0006511
GO:0008270
GO:0016567
GO:0016740
GO:0030163
GO:0031461
GO:0031466
GO:0036211
GO:0043226
GO:0045116
GO:0046872
GO:0061630
GO:0061663
GO:0097602
GO:0140096
Participates
as a component of
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Drosophila melanogaster)
CRL5 E3 ubiquitin ligase [cytosol] (Drosophila melanogaster)
NEDD8-CRL5 E3 ligase [cytosol] (Drosophila melanogaster)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Drosophila melanogaster)
Inferred From
RNF7 (RBX2) [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_610691.1
,
NP_001163119.1
Flybase
FBgn0044020
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