Reactome | RpL36 [cytosol]

RpL36 [cytosol]

Stable Identifier

R-DME-72464

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

RPL36, P49630

Locations in the PathwayBrowser

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Metabolism of RNA (Drosophila melanogaster)

- Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpL36 [cytosol] (Drosophila melanogaster)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpL36 [cytosol] (Drosophila melanogaster)
    - SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpL36 [cytosol] (Drosophila melanogaster)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Drosophila melanogaster)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Drosophila melanogaster)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpL36 [cytosol] (Drosophila melanogaster)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpL36 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P49630

Gene Names

RpL36

Reference Genes

BioGPS Gene:31009 RpL36

ENSEMBL:FBgn0002579

FlyBase:FBgn0002579

KEGG:dme:Dmel_CG7622 RpL36

Monarch:31009 RpL36

NCBI Gene:31009 RpL36

UCSC:P49630 RpL36

Reference Transcript

Other Identifiers

152271_at

1624019_s_at

31009

GO:0000228

GO:0002181

GO:0003735

GO:0005198

GO:0005694

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0022625

GO:0022626

GO:1990904

Participates

as a component of

Inferred From

RPL36 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001284750.1, NP_726688.1, NP_726686.1, NP_726687.1, NP_476629.1

ENSEMBL

FBtr0070156, FBtr0070155, FBtr0070157, FBtr0070158, FBtr0345321, FBpp0070150, FBgn0002579, FBpp0070153, FBpp0311481, FBpp0070151, FBpp0070152

FlyBase

FBgn0002579

PRO

P49630

PDB

6XU8, 6XU7, 6XU6, 4V6W

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