Reactome | RpLP0 [cytosol]

RpLP0 [cytosol]

Stable Identifier

R-DME-72396

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

RPLP0, P19889

Locations in the PathwayBrowser

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Metabolism of RNA (Drosophila melanogaster)

- Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpLP0 [cytosol] (Drosophila melanogaster)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpLP0 [cytosol] (Drosophila melanogaster)
    - SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpLP0 [cytosol] (Drosophila melanogaster)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Drosophila melanogaster)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Drosophila melanogaster)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpLP0 [cytosol] (Drosophila melanogaster)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        60S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpLP0 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P19889

Gene Names

RpLP0

Reference Genes

BioGPS Gene:40451 RpLP0

ENSEMBL:FBgn0000100

FlyBase:FBgn0000100

KEGG:dme:Dmel_CG7490 RpLP0

Monarch:40451 RpLP0

NCBI Gene:40451 RpLP0

UCSC:P19889 RpLP0

Reference Transcript

Other Identifiers

143074_at

1637546_at

40451

GO:0000027

GO:0000287

GO:0002181

GO:0003723

GO:0003735

GO:0003824

GO:0005198

GO:0005509

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005840

GO:0006281

GO:0006284

GO:0006974

GO:0016363

GO:0016787

GO:0022625

GO:0022626

GO:0042254

GO:0052720

GO:0065003

GO:0070180

GO:0090304

GO:0140097

GO:1990904

Participates

as a component of

Inferred From

RPLP0 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_524211.1, NP_001262202.1

ENSEMBL

FBtr0334113, FBtr0078481, FBpp0306232, FBgn0000100, FBpp0078134

FlyBase

FBgn0000100

PRO

P19889

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