Reactome | RpS19a [cytosol]

RpS19a [cytosol]

Stable Identifier

R-DME-72343

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

RPS19, P39018

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Drosophila melanogaster)

- Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        40S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpS19a [cytosol] (Drosophila melanogaster)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        40S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpS19a [cytosol] (Drosophila melanogaster)
    - SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        40S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpS19a [cytosol] (Drosophila melanogaster)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Drosophila melanogaster)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Drosophila melanogaster)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        40S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpS19a [cytosol] (Drosophila melanogaster)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Drosophila melanogaster)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Drosophila melanogaster)
        
        80S ribosome [cytosol] (Drosophila melanogaster)
        
        40S ribosomal complex [cytosol] (Drosophila melanogaster)
        
        RpS19a [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P39018

Gene Names

RpS19a

Reference Genes

BioGPS Gene:32635 RpS19a

ENSEMBL:FBgn0010412

FlyBase:FBgn0010412

KEGG:dme:Dmel_CG4464 RpS19a

Monarch:32635 RpS19a

NCBI Gene:32635 RpS19a

UCSC:P39018 RpS19a

Reference Transcript

Other Identifiers

143619_at

1637448_s_at

32635

GO:0000028

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0022626

GO:0022627

GO:0065003

GO:1990904

Participates

as a component of

Other forms of this molecule

RpS19a [nucleoplasm]

Inferred From

RPS19 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001285338.1, NP_523376.1, NP_001285339.1, NP_727992.1, NP_727993.1

ENSEMBL

FBpp0074086, FBpp0074087, FBpp0074088, FBpp0309135, FBgn0010412, FBtr0345129, FBpp0311350, FBtr0340149, FBtr0074311, FBtr0074313, FBtr0074312

FlyBase

FBgn0010412

PRO

P39018

PDB

6XU8, 6XU7, 6XU6, 4V6W

Cite Us!