Reactome | tra2 [nucleoplasm]

tra2 [nucleoplasm]

Stable Identifier

R-DME-71939

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

RBMX, P19018

Locations in the PathwayBrowser

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Metabolism of RNA (Drosophila melanogaster)

- Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
  - Formation of pre-mRNPs (Drosophila melanogaster)
    - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
      - tra2 [nucleoplasm] (Drosophila melanogaster)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
      - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
  - mRNA 3'-end processing (Drosophila melanogaster)
    - mRNA Polyadenylation (Drosophila melanogaster)
      - Core CPA complex binds capped pre-mRNA (Drosophila melanogaster)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - PP1 dephosphorylates RNA Pol II (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - RBBP6 activates CPSF complex (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
  - mRNA Splicing (Drosophila melanogaster)
    - mRNA Splicing - Major Pathway (Drosophila melanogaster)
      - Formation of the Spliceosomal B* complex (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal Bact complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C complex containing intron lariat (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C* complex (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal P complex [nucleoplasm] (Drosophila melanogaster)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        tra2 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P19018

Gene Names

tra2

Reference Genes

BioGPS Gene:36619 tra2

CTD Gene:36619 tra2

ENSEMBL:FBgn0003742

FlyBase:FBgn0003742

KEGG:dme:Dmel_CG10128 tra2

Monarch:36619 tra2

NCBI Gene:36619 tra2

UCSC:P19018 tra2

Reference Transcript

Other Identifiers

141588_at

1639205_s_at

36619

GO:0000245

GO:0000381

GO:0000398

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005681

GO:0006397

GO:0007283

GO:0007530

GO:0007548

GO:0008380

GO:0016071

GO:0019101

GO:0019102

GO:0022414

GO:0030154

GO:0030237

GO:0036002

GO:0042802

GO:0048026

GO:0065003

GO:0071011

Participates

as a member of

Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

tra2 [cytosol]

tra2 [nucleoplasm]

Inferred From

RBMX [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_476764.1, NP_599107.1, NP_476763.1, NP_476766.1, NP_995834.1, NP_995835.1, NP_476765.1

ENSEMBL

FBtr0089620, FBtr0089621, FBtr0089617, FBgn0003742, FBpp0088562, FBpp0088947, FBpp0088946

FlyBase

FBgn0003742

PRO

P19018

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