Reactome | CG18656 [nucleoplasm]

CG18656 [nucleoplasm]

Stable Identifier

R-DME-71933

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

HNRNPC, Q7KU81

Locations in the PathwayBrowser

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Metabolism of RNA (Drosophila melanogaster)

- Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
  - Formation of pre-mRNPs (Drosophila melanogaster)
    - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
      - nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
      - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
  - mRNA 3'-end processing (Drosophila melanogaster)
    - mRNA Polyadenylation (Drosophila melanogaster)
      - Core CPA complex binds capped pre-mRNA (Drosophila melanogaster)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - PP1 dephosphorylates RNA Pol II (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - RBBP6 activates CPSF complex (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
  - mRNA Splicing (Drosophila melanogaster)
    - mRNA Splicing - Major Pathway (Drosophila melanogaster)
      - Formation of the Spliceosomal B* complex (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal Bact complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C complex containing intron lariat (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C* complex (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal P complex [nucleoplasm] (Drosophila melanogaster)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)
        
        CG18656 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7KU81

Gene Names

CG18656

Reference Genes

BioGPS Gene:2768945 CG18656

ENSEMBL:FBgn0259935

FlyBase:FBgn0259935

KEGG:dme:Dmel_CG42458 CG18656

Monarch:2768945 CG18656

NCBI Gene:2768945 CG18656

UCSC:Q7KU81 CG18656

Reference Transcript

RefSeq:NM_206288.4 CG18656

Other Identifiers

142355_at

1625668_at

1627283_at

1636802_at

2768945

GO:0003676

GO:0003723

GO:0005634

GO:0005829

GO:0043489

Participates

as a member of

nonshuttling HNRNPs [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

CG18656 [cytosol]

Inferred From

HNRNPC [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_996010.2

FlyBase

FBgn0259935

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