Reactome | hig [endoplasmic reticulum-Golgi intermediate compartment membrane]

hig [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-DME-6807756-3

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

GPI-CD55, Q09101

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Asparagine N-linked glycosylation (Drosophila melanogaster)
    - Transport to the Golgi and subsequent modification (Drosophila melanogaster)
      - ER to Golgi Anterograde Transport (Drosophila melanogaster)
        
        COPI-mediated anterograde transport (Drosophila melanogaster)
        
        ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Drosophila melanogaster)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of GPI-CD55 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        hig [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of GPI-CD55 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        hig [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        ARFGAPs stimulate ARF GTPase activity (Drosophila melanogaster)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of GPI-CD55 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        hig [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q09101

Gene Names

hig

Reference Genes

BioGPS Gene:35949 HIG

CTD Gene:35949 HIG

ENSEMBL:FBgn0010114

FlyBase:FBgn0010114

KEGG:dme:Dmel_CG2040 HIG

Monarch:35949 HIG

NCBI Gene:35949 HIG

UCSC:Q09101 HIG

Reference Transcript

Participates

as a member of

Homologues of GPI-CD55 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Other forms of this molecule

hig [extracellular region]

hig [platelet dense granule membrane]

hig [platelet alpha granule membrane]

hig [extracellular region]

hig [platelet dense granule lumen]

hig [plasma membrane]

hig [Golgi membrane]

hig [transport vesicle]

hig [ficolin-1-rich granule membrane]

hig [plasma membrane]

hig [secretory granule membrane]

hig [plasma membrane]

Inferred From

GPI-CD55 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Modified Residues

Name

L-serine amide (GPI-anchor amidated amino acid carboxyl end residue(1−)) at 353 (in Homo sapiens)

Coordinate

353

Modification

GPI-anchor amidated amino acid carboxyl end residue(1−)

PsiMod Name

L-serine amide

PsiMod Definition

A protein modification that effectively converts an L-serine residue to L-serine amide.

Cross References

RefSeq

NP_724772.1, NP_724773.1, NP_525110.2, NP_001014514.1

ENSEMBL

FBtr0088607, FBpp0087688, FBgn0010114

FlyBase

FBgn0010114

PRO

Q09101

GlyGen

Q09101